GRIN2C anticorps (pSer1244)

N° du produit ABIN6658214

N° du produit (Fournisseur): 600-401-d96

Cet anticorps anti-GRIN2C est un anticorps Lapin Polyclonal détectant GRIN2C dans WB. Adapté pour Rat.

Aperçu rapide pour GRIN2C anticorps (pSer1244) (ABIN6658214)

Antigène: GRIN2C (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2c (GRIN2C))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GRIN2C est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-GRIN2C anticorps

Épitope: pSer1244

N° du produit (Fournisseur): 600-401-d96

Fournisseur: Rockland

Fonction: NMDA R2C phospho S1244 Antibody

Réactivité croisée (Details): Anti-NMDA R2C pS1244 antibody is directed against NMDA R2C protein.

Purification: The antibody was affinity purified from monospecific antiserum by immunoaffinity purification and is specific for the phosphorylated NMDA R2C protein.

Immunogène: Anti-NMDA R2C pS1244 Antibody was produced by repeated immunizations with synthetic phospho-peptide corresponding to amino acid residues surrounding Ser1244.

Isotype: IgG

Information d'application

Indications d'application:

Western_Blot_Dilution: 1:1000

Other: User Optimized

Commentaires:

Anti-NMDA R2C pS1244 Antibody is tested for use in Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 140 kDa in size corresponding to the NMDA receptor phosphorylated at Ser1244 in the appropriate cell lysate or extract.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer:

Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Date de péremption: 12 months

Détails sur GRIN2C

Antigène: GRIN2C (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2c (GRIN2C))

Autre désignation: NMDA R2C

Sujet:

Synonyms: Glutamate [NMDA] receptor subunit epsilon-3, N-methyl D-aspartate receptor subtype 2C, NMDAR2C, NR2C

Background: NMDA R2C pS1244 Antibody detects phophorylated NMDA R2C protein. The ion channels activated by glutamate that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR). The NMDAR plays an essential role in memory, neuronal development and it has also been implicated in several disorders of the central nervous system including Alzheimer's, epilepsy and ischemic neuronal cell death. The NMDA receptor is also one of the principal molecular targets for alcohol in the CNS. The NMDAR is also potentiated by protein phosphorylation. The NR2C subunit of the receptor is thought to influence the NMDAR conductance level. Phosphorylation of Ser1244 has been shown to regulate NMDA receptor channel function. Anti-NMDA R2C pS1244 Antibody is ideal for investigators involved in Neuroscience, Signal Transduction, and Cell Signaling Research.

Gene Name: GRIN2C

ID gène: 24411

UniProt: Q00961

Pathways: Synaptic Membrane