GRIN2C anticorps (AA 567-595)

N° du produit ABIN1881390

Détail du produit anti-GRIN2C anticorps

Antigène: GRIN2C (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2c (GRIN2C))

Épitope: AA 567-595

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GRIN2C est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This GRIN2C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 567-595 amino acids from the Central region of human GRIN2C.

Clone: RB40514

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-GRIN2C (ABIN1881390)

Need, Keefe, Ge, Grossman, Dickson, McEvoy, Goldstein: "Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis." dans: European journal of human genetics : EJHG, Vol. 17, Issue 7, pp. 946-57, (2009) (PubMed).

Krapivinsky, Krapivinsky, Manasian, Ivanov, Tyzio, Pellegrino, Ben-Ari, Clapham, Medina: "The NMDA receptor is coupled to the ERK pathway by a direct interaction between NR2B and RasGRF1." dans: Neuron, Vol. 40, Issue 4, pp. 775-84, (2003) (PubMed).

Self, Mulholland, Nath, Harris, Prendergast: "The human immunodeficiency virus type-1 transcription factor Tat produces elevations in intracellular Ca2+ that require function of an N-methyl-D-aspartate receptor polyamine-sensitive site." dans: Brain research, Vol. 995, Issue 1, pp. 39-45, (2003) (PubMed).

Détails sur GRIN2C

Antigène: GRIN2C (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2c (GRIN2C))

Autre désignation: GRIN2C (GRIN2C Produits)

Synonymes: anticorps GRIN2C, anticorps NMDAR2C, anticorps il12rb2l, anticorps il-12rb2.b, anticorps nr2c, anticorps GluN2C, anticorps NR2C, anticorps glutamate ionotropic receptor NMDA type subunit 2C, anticorps interleukin 12 receptor, beta 2a, like, anticorps glutamate receptor, ionotropic, N-methyl D-aspartate 2C S homeolog, anticorps glutamate receptor, ionotropic, N-methyl D-aspartate 2C, anticorps glutamate receptor, ionotropic, NMDA2C (epsilon 3), anticorps GRIN2C, anticorps il12rb2l, anticorps grin2c.S, anticorps grin2c, anticorps Grin2c

Sujet: N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C), and NMDAR2D (GRIN2D). [provided by RefSeq].

Poids moléculaire: 134209

NCBI Accession: NP_000826

UniProt: Q14957

Pathways: Synaptic Membrane