GABRA3 anticorps (N-Term)

N° du produit ABIN6658232

N° du produit (Fournisseur): 600-401-d46

Cet anticorps anti-GABRA3 est un anticorps Lapin Polyclonal détectant GABRA3 dans WB et IHC. Adapté pour Rat.

Aperçu rapide pour GABRA3 anticorps (N-Term) (ABIN6658232)

Antigène: GABRA3 (gamma-aminobutyric Acid (GABA) A Receptor, alpha 3 (GABRA3))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GABRA3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-GABRA3 anticorps

Épitope: N-Term

N° du produit (Fournisseur): 600-401-d46

Fournisseur: Rockland

Fonction: GABA(A) Receptor alpha 3 Antibody

Réactivité croisée (Details): Anti-GABA(A) Receptor alpha 3 antibody is directed against human GABA(A) Receptor alpha 3.

Purification: The antibody was affinity purified from monospecific antibodies by immunoaffinity purification.

Immunogène: Anti-GABA(A) Receptor alpha 3 Antibody was produced by repeated immunizations with a synthetic peptide from the N-terminal region of the alpha 3 subunit of rat GABAA.

Isotype: IgG

Information d'application

Indications d'application:

Immunohistochemistry_Dilution: 1:100

Western_Blot_Dilution: 1:1000

Commentaires:

Anti-GABA(A) Receptor alpha 3 (Rabbit) antibody is tested for use in Western Blotting and IHC. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 51 kDa in size corresponding to the alpha 3 subunit of the GABA(A) receptor in the appropriate cell lysate or extract.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer:

Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Date de péremption: 12 months

Détails sur GABRA3

Antigène: GABRA3 (gamma-aminobutyric Acid (GABA) A Receptor, alpha 3 (GABRA3))

Autre désignation: GABA(A) Receptor alpha 3

Sujet:

Synonyms: Gamma-aminobutyric acid receptor subunit alpha-3, GABA(A) receptor subunit alpha-3

Background: GABA(A) Receptor alpha 3 antibody detects GABA(A) Receptor alpha 3. Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a Cl- channel associated with the GABAA receptor (GABAA-R) subtype. GABAA-Rs are important therapeutic targets for a range of sedative, anxiolytic, and hypnotic agents and are implicated in several diseases including epilepsy, anxiety, depression, and substance abuse. The GABAA-R is a multimeric subunit complex. To date six αs, four βs and four γs, plus alternative splicing variants of some of these subunits, have been identified. Injection in oocytes or mammalian cell lines of cRNA coding for α- and β-subunits results in the expression of functional GABAA-Rs sensitive to GABA. However, coexpression of a γ-subunit is required for benzodiazepine modulation. The various effects of the benzodiazepines in brain may also be mediated via different α-subunits of the receptor. Anti-GABA(A) Receptor alpha 3 Antibody is ideal for investigators involved in Neuroscience.

Gene Name: GABRA3

ID gène: 24947

NCBI Accession: NP_058765

UniProt: P20236