Tyrosine Hydroxylase anticorps (pSer31)

N° du produit ABIN6658241

N° du produit (Fournisseur): 600-401-e51

Cet anticorps anti-Tyrosine Hydroxylase est un anticorps Lapin Polyclonal détectant Tyrosine Hydroxylase dans WB, IHC et FM. Adapté pour Rat.

Aperçu rapide pour Tyrosine Hydroxylase anticorps (pSer31) (ABIN6658241)

Antigène: Tyrosine Hydroxylase (TH)

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Tyrosine Hydroxylase est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Fluorescence Microscopy (FM)

Détail du produit anti-Tyrosine Hydroxylase anticorps

Épitope: pSer31

N° du produit (Fournisseur): 600-401-e51

Fournisseur: Rockland

Fonction: Tyrosine Hydroxylase phospho S31 Antibody

Réactivité croisée (Details): Anti-Tyrosine Hydroxylase pS31 Antibody is directed against phosphorylated rat Tyrosine Hydroxylase protein.

Purification: Tyrosine Hydroxylase pS31 antibodies are affinity purified from monospecific antiserum by immunoaffinity purification.

Immunogène: Anti-Tyrosine Hydroxylase pS31 Antibody was produced repeated immunizations with a synthetic phospho-peptide corresponding to amino acid residues surrounding Ser31.

Isotype: IgG

Information d'application

Indications d'application:

Immunohistochemistry_Dilution: 1:1000

IF_Microscopy_Dilution: 1:1000

Western_Blot_Dilution: 1:1000

Other: User Optimized

Commentaires:

Anti-Tyrosine Hydroxylase pS31 (Rabbit) antibody is tested for use in Western Blotting, IHC and ICC. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 60 kDa in size corresponding to tyrosine hydroxylase protein phosphorylated at Ser31 in the appropriate cell lysate or extract.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer:

Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Date de péremption: 12 months

Détails sur Tyrosine Hydroxylase

Antigène: Tyrosine Hydroxylase (TH)

Autre désignation: Tyrosine Hydroxylase

Sujet:

Synonyms: Tyrosine 3-monooxygenase, Tyrosine 3-hydroxylase, TH

Background: Tyrosine Hydroxylase pS31 Antibody detects phosphorylated Tyrosine Hydroxylase protein. Tyrosine hydroxylase (TH) is the rate-limiting enzyme in the synthesis of the catecholamines dopamine and norepinephrine. TH antibodies can therefore be used as markers for dopaminergic and noradrenergic neurons in a variety of applications including depression, schizophrenia, Parkinson's disease and drug abuse. TH antibodies can also be used to explore basic mechanisms of dopamine and norepinephrine signaling. The activity of TH is also regulated by phosphorylation. Phospho-specific antibodies for the phosphorylation sites on TH can be used to great effect in studying this regulation and in identifying the cells in which TH phosphorylation occurs.

Gene Name: TH

ID gène: 25085

UniProt: P04177

Pathways: Dopaminergic Neurogenesis, Response to Water Deprivation, Sensory Perception of Sound, Carbohydrate Homeostasis, Feeding Behaviour