RPH3A anticorps (C-Term)

N° du produit ABIN6658251

Détail du produit anti-RPH3A anticorps

Antigène: RPH3A (Rabphilin 3A (RPH3A))

Épitope: C-Term

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RPH3A est non-conjugé

Application: Western Blotting (WB)

Réactivité croisée (Details): Cross reactivity with Rab 3A from other species has not been determined, however, the sequence of the immunogen shows 100 % identity to mouse, human, bovine, canine, and non-human primates, therefore, cross reactivity is expected.

Purification: Anti-Rabphilin 3A antibody is directed against rat rabphilin 3A proteins. Anti-Rabphilin 3A antibodies are affinity purified from monospecific antiserum by immunoaffinity purification.

Immunogène:

Immunogen: Anti-Rabphilin 3A Antibody was produced in rabbit by repeated immunizations with synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH.

Immunogen Type: Peptide

Isotype: IgG

Information d'application

Indications d'application:

Application Note: Anti-Rabphilin 3A (Rabbit) antibody is suitable for use in ELISA, and in western blotting. Expect a band of approximately 82 kDa in size corresponding to rabphilin 3A protein in the appropriate cell lysate or extract. Researchers should determine optimal titers for applications that are not stated below.

Western Blot Dilution: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer:

Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

Stock: RT,4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening.  Aliquot contents and freeze at -20° C or below for extended storage.  Avoid cycles of freezing and thawing.  Centrifuge product if not completely clear after standing at room temperature.  This product is stable for several weeks at 4° C as an undiluted liquid.  Dilute only prior to immediate use.

Détails sur RPH3A

Antigène: RPH3A (Rabphilin 3A (RPH3A))

Autre désignation: Rabphilin 3A (RPH3A Produits)

Synonymes: anticorps 2900002P20Rik, anticorps AU022689, anticorps AW108370, anticorps CG11556, anticorps Dmel\\CG11556, anticorps exophilin-1, anticorps fc61h10, anticorps rph3a, anticorps wu:fc61h10, anticorps rabphilin 3A, anticorps Rabphilin, anticorps rabphilin-3a, putative, anticorps rabphilin-3A, anticorps rabphilin 3A S homeolog, anticorps rabphilin 3A homolog (mouse), a, anticorps RPH3A, anticorps Rph3a, anticorps Rph, anticorps Smp_145120, anticorps Tsp_00335, anticorps rph3a.S, anticorps rph3aa

Sujet:

Synonyms: Rabphilin 3A Homolog, Rabphilin-3A, RP3A, Rph3A, Exophilin 1, Exophilin-1

Background: Rabphilin 3A antibody detects Rab 3A which is a peripheral membrane protein that binds Ca2+ and phospholipids and is attached to synaptic vesicle membranes. The expression of rabphilin 3A is reduced in an animal model of Huntington's disease. Rabphilin can be phosphorylated at Ser234 by both CAM kinase II and PKA and this phosphorylation has been suggested to regulate neuronal activity during development in a synapse-specific manner. Anti-Rabphilin 3A antibody is ideal for investigators involved in Signal Transduction, Cell Signaling, and Neuroscience research.

Gene Name: RPH3A

ID gène: 171039

UniProt: P47709

Pathways: Synaptic Vesicle Exocytosis