ADRB1 anticorps (AA 181-250)

N° du produit ABIN669351

Détail du produit anti-ADRB1 anticorps

Antigène: ADRB1 (Adrenergic, beta-1-, Receptor (ADRB1))

Épitope: AA 181-250

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ADRB1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Réactivité croisée: Humain, Souris, Rat

Homologie: Dog,Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human ADRB1

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-ADRB1 (ABIN669351)

Bornholz, Benninghaus, Reinke, Felix, Roggenbuck, Jahns-Boivin, Jahns, Boege: "A standardised FACS assay based on native, receptor transfected cells for the clinical diagnosis and monitoring of ?1-adrenergic receptor autoantibodies in human heart disease." dans: Clinical chemistry and laboratory medicine : CCLM / FESCC, (2015) (PubMed).

Deng, Liu, Zhang, Wang, Peng, Wei, Jiang: "Exogenous norepinephrine attenuates the efficacy of sunitinib in a mouse cancer model." dans: Journal of experimental & clinical cancer research : CR, Vol. 33, pp. 21, (2014) (PubMed).

Détails sur ADRB1

Antigène: ADRB1 (Adrenergic, beta-1-, Receptor (ADRB1))

Autre désignation: ADRB1 (ADRB1 Produits)

Synonymes: anticorps ADRB1R, anticorps B1AR, anticorps BETA1AR, anticorps RHR, anticorps RATB1AR, anticorps X-Beta1AR, anticorps BAR1, anticorps zgc:194728, anticorps zgc:194731, anticorps ADRB1, anticorps Adrb-1, anticorps beta-AR, anticorps adrenoceptor beta 1, anticorps adrenoceptor beta 1 L homeolog, anticorps adrenergic, beta-1-, receptor, anticorps adrenergic receptor, beta 1, anticorps ADRB1, anticorps Adrb1, anticorps adrb1.L, anticorps adrb1

Sujet:

Synonyms: RHR, B1AR, ADRB1R, BETA1AR, Beta-1 adrenergic receptor, Beta-1 adrenoreceptor, Beta-1 adrenoceptor, ADRB1

Background: Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity. Mediates Ras activation through G(s)-alpha- and cAMP-mediated signaling.

ID gène: 153

UniProt: P08588

Pathways: cAMP Metabolic Process, Cellular Glucan Metabolic Process, Regulation of Muscle Cell Differentiation, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Brown Fat Cell Differentiation