IL-18 anticorps
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- Antigène Voir toutes IL-18 (IL18) Anticorps
- IL-18 (IL18) (Interleukin 18 (IL18))
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Reactivité
- Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp IL-18 est non-conjugé
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Application
- Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Réactivité croisée
- Souris, Rat
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from rat IL-18
- Isotype
- IgG
- Top Product
- Discover our top product IL18 Anticorps primaire
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- Indications d'application
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IHC-P 1:200-400
IF(IHC-P) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- IL-18 (IL18) (Interleukin 18 (IL18))
- Autre désignation
- IL-18 (IL18 Produits)
- Synonymes
- anticorps Igif, anticorps Il-18, anticorps IL-18, anticorps IGIF, anticorps ChIL-18, anticorps IL-1g, anticorps IL1F4, anticorps IL18, anticorps interleukin 18, anticorps Il18, anticorps IL18
- Sujet
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Synonyms: interferon gamma-inducing factor IG, Interferon gamma-inducing factor, N-gamma-inducing factor, Interleukin-1 gamma, Iboctadekin, N gamma inducing factor, IG, IL 1 gamma, IL 18, IL 1g, IL1 gamma, IL18 protein, IL1F4, IL1g, IL1gamma, IL4, Interferon gamma inducing factor, Interleukin 1 gamma, Interleukin 18, Interleukin18, MGC12320, IL18_MOUSE.
Background: IL18 (IFN-gamma-inducing factor, IGIF) is a novel pro-inflammatory cytokine that augments natural killer (NK) activity in spleen cells.This cytokine can induce the IFN-gamma production of T cells. The combination of this cytokine and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its biological activity.IL18 also has other biological properties such as stimulation of Fas ligand expression, and induction of CC and CXC chemokines. IL18 increases production of competent HIV. IL18 is related to the IL1 family. One of the IL18 receptor chains is the IL1 receptor-related protein, a member of the IL 1R family. Like IL1 , IL18 is first synthesized as a leaderless precursor requiring the IL1 converting enzyme (ICE) for cleavage into an active molecule. IL18 may play a role in tissue injury in inflammatory reactions.
- ID gène
- 29197
- Pathways
- Cellular Response to Molecule of Bacterial Origin, Activated T Cell Proliferation, Cancer Immune Checkpoints, Inflammasome
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