TUBB3 anticorps

N° du produit ABIN6699201

N° du produit (Fournisseur): 212-301-e55

Cet anticorps Souris Monoclonal détecte spécifiquement TUBB3 dans WB et IHC. Il présente une réactivité envers Rat.

Aperçu rapide pour TUBB3 anticorps (ABIN6699201)

Antigène: TUBB3 (Tubulin, beta 3 (TUBB3))

Reactivité: Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TUBB3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: AA10

Détail du produit anti-TUBB3 anticorps

N° du produit (Fournisseur): 212-301-e55

Fournisseur: Rockland

Fonction: Tubulin beta 3 Antibody

Réactivité croisée (Details): Anti-Tubulin beta 3 Antibody is directed against rat Tubulin beta III protein.

Purification: The antibody was Protein G purified from cell culture supernatant.

Immunogène: Anti-Tubulin beta 3 Monoclonal Antibody was produced by repeated immunizations with a synthetic peptide corresponding to amino acid residues specific to beta III tubulin.

Isotype: IgG

Information d'application

Indications d'application:

Immunohistochemistry_Dilution: 1:1,000

Western_Blot_Dilution: 1:10,000

Other: User Optimized

Commentaires:

Anti-Tubulin beta 3 (Mouse) antibody is tested for use in Western Blotting and IHC. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 55 kDa in size corresponding to beta III tubulin proteins in the appropriate cell lysate or extract.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer:

Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Date de péremption: 12 months

Détails sur TUBB3

Antigène: TUBB3 (Tubulin, beta 3 (TUBB3))

Autre désignation: Tubulin beta 3

Sujet:

Synonyms: mouse anti-Tubulin beta 3 Antibody, Neuron-specific class III beta-tubulin, Tubulin beta-3 chain, Tubulin beta-4 chain, Tubulin beta-III

Background: Tubulin beta 3 Antibody detects Tubulin beta III protein. Tubulin is the major constituent of microtubules, existing as a heterodimer of the α and β subunits. The beta III isoform of tubulin is found almost exclusively in neuronal processes of adult tissues and is therefore an excellent marker for neurons. Neuron specific, posttranslational modifications within the C-terminal domain of beta III tubulin have been shown to be developmentally regulated suggesting that they may serve to modulate the interaction of tubulin with microtubule associated proteins. Additionally, beta III tubulin has been found to be highly expressed in cancer cells such as small cell lung cancer, large cell neuroendocrine carcinoma and adenocarcinomas and is correlated with an increasing histological degree of malignancy.

Gene Name: TUBB3

ID gène: 246118

UniProt: Q4QRB4

Pathways: Dynamique des Microtubules, M Phase