DPPA2 anticorps (FITC)

N° du produit ABIN670663

Cet anticorps Lapin Polyclonal détecte spécifiquement DPPA2 dans IF (p). Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour DPPA2 anticorps (FITC) (ABIN670663)

Antigène: DPPA2 (Developmental Pluripotency Associated 2 (DPPA2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DPPA2 est conjugé à/à la FITC

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-DPPA2 anticorps (FITC)

Homologie: Human,Mouse,Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from mouse DPPA2

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur DPPA2

Antigène: DPPA2 (Developmental Pluripotency Associated 2 (DPPA2))

Autre désignation: DPPA2

Sujet:

Synonyms: Developmental Pluripotency Associated 2, developmental pluripotency associated gene2, PESCRG1, Pluripotent embryonic stem cell related protein 1, cancer/testis antigen 100, CT100, developmental pluripotency-associated gene 2, developmental pluripotency-associated protein 2, ECAT15-2, embryonic stem cell ESC associated transcript 15-2, PESCRG1, Pluripotent embryonic stem cell related protein 1, Pluripotent embryonic stem cell-related gene 1, Pluripotent embryonic stem cell-related gene 1 protein .

Background: SCRG1 (scrapie-responsive protein 1) is a 98 amino acid secreted protein that belongs to the SCRG1 family. The SCRG1 protein contains a 20-amino acid signal peptide, and is expressed abundantly in the central nervous system of human adult, but not at all in fetal brain. The protein is targeted to the Golgi apparatus and large dense-core vesicles/secretory granules in neurons. High levels of SCRG1 transcripts are also observed in testis and aorta. SCRG1 is associated with neurodegenerative changes observed in transmissible spongiform encephalopathies. It may play a role in host response to prion-associated infections. The SCRG1 protein may be partly included in the membrane or secreted by the cells due to its hydrophobic N-terminus. The human and mouse SCRG1 proteins share 83 % sequence identity. The SCRG1 gene is conserved in chimpanzee, cow, mouse, rat and chicken, and maps to human chromosome 4q34.1.

ID gène: 151871

Pathways: Stem Cell Maintenance