CFP anticorps

N° du produit ABIN6719298

Cet anticorps anti-CFP est un anticorps Lapin Polyclonal détectant CFP dans WB, IHC, FACS et IHC (fro). Adapté pour Humain, Souris et Rat.

Aperçu rapide pour CFP anticorps (ABIN6719298)

Antigène: CFP (Complement Factor P (CFP))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CFP est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-CFP anticorps

Fonction: Anti-CFP Antibody Picoband®

Séquence: MVEGQGEKNV TFWGRPLPRC EELQGQKLVV EEKR

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-CFP Antibody Picoband® (ABIN6719298). Tested in Flow Cytometry, IHC, IHC-F, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human CFP, which shares 86.1% amino acid (aa) sequence identity with both mouse and rat CFP.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
Immunohistochemistry (Frozen Section), 0.5-1 μg/mL
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells
1. Ash, S., Johnson, C., Shohat, M., Shohat, T., Schlesinger, M. Further mapping of the properdin deficiency gene in a Tunisian Jewish family--evidence for genetic homogeneity. Isr. J. Med. Sci. 30: 626-628, 1994. 2. Coleman, M. P., Murray, J. C., Willard, H. F., Nolan, K. F., Reid, K. B. M., Blake, D. J., Lindsay, S., Bhattacharya, S. S., Wright, A., Davies, K. E. Genetic and physical mapping around the properdin P gene. Genomics 11: 991-996, 1991.

Commentaires:

Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Détails sur CFP

Antigène: CFP (Complement Factor P (CFP))

Autre désignation: CFP

Sujet:

Synonyms: Properdin, Complement factor P, CFP, PFC

Tissue Specificity: Widely expressed.

Background: Properdin (factor P) is a plasma protein that is active in the alternative complement pathway of the innate immune system. It is mapped to Xp11.23. This protein binds to many microbial surfaces and apoptotic cells and stabilizes the C3- and C5-convertase enzyme complexes in a feedback loop that ultimately leads to formation of the membrane attack complex and lysis of the target cell. Mutations in this gene result in two forms of properdin deficiency, which results in high susceptibility to meningococcal infections. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Poids moléculaire: 51 kDa

ID gène: 5199

UniProt: P27918

Pathways: Système du Complément