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TXN anticorps (AA 2-105)

L’anticorps Lapin Polyclonal anti-TXN a été validé pour WB, IHC, ELISA, ICC et IF. Il convient pour détecter TXN dans des échantillons de Rat et Souris.
N° du produit ABIN6719381

Aperçu rapide pour TXN anticorps (AA 2-105) (ABIN6719381)

Antigène

Voir toutes TXN Anticorps
TXN (Thioredoxin (TXN))

Reactivité

  • 77
  • 25
  • 23
  • 8
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Rat, Souris

Hôte

  • 81
  • 23
Lapin

Clonalité

  • 70
  • 34
Polyclonal

Conjugué

  • 50
  • 15
  • 12
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
Cet anticorp TXN est non-conjugé

Application

  • 72
  • 38
  • 30
  • 24
  • 16
  • 12
  • 10
  • 4
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
  • Épitope

    • 22
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 2-105

    Fonction

    Anti-Thioredoxin/TRX/Txn Antibody Picoband®

    Réactivité croisée (Details)

    No cross-reactivity with other proteins.

    Attributs du produit

    Anti-Thioredoxin/TRX/Txn Antibody Picoband® (ABIN6719381). Tested in ELISA, IF, IHC, ICC, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Purification

    Immunogen affinity purified.

    Immunogène

    E. coli-derived mouse Thioredoxin TRX recombinant protein (Position: V2-A105).

    Isotype

    IgG
  • Indications d'application

    Western blot, 0.1-0.5 μg/mL
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
    Immunocytochemistry/Immunofluorescence, 2 μg/mL
    ELISA, 0.1-0.5 μg/mL
    1. Benhar, M., Forrester, M. T., Hess, D. T., Stamler, J. S. Regulated protein denitrosylation by cytosolic and mitochondrial thioredoxins. Science 320: 1050-1054, 2008. 2. Im, J.-Y., Lee, K.-W., Woo, J.-M., Junn, E., Mouradian, M. M. DJ-1 induces thioredoxin 1 expression through the Nrf2 pathway. Hum. Molec. Genet. 21: 3013-3024, 2012.

    Commentaires

    Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Concentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Antigène

    TXN (Thioredoxin (TXN))

    Autre désignation

    Txn

    Sujet

    Synonyms: Thioredoxin, Trx, ATL-derived factor, ADF, Txn, Txn1

    Tissue Specificity: Colon, small intestine, colonic tumors, bronchus, cervix and gall bladder.

    Background: Thioredoxin is a class of small redox proteins known to be present in all organisms. It is mapped to 9q31.3. The protein encoded by this gene acts as a homodimer and is involved in many redox reactions. The encoded protein is active in the reversible S-nitrosylation of cysteines in certain proteins, which is part of the response to intracellular nitric oxide. This protein is found in the cytoplasm. Two transcript variants encoding different isoforms have been found for this gene.

    Poids moléculaire

    12 kDa

    ID gène

    22166

    UniProt

    P10639

    Pathways

    Carbohydrate Homeostasis, Cell RedoxHomeostasis
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