INPPL1 anticorps (AA 1172-1258)

N° du produit ABIN6719492

Détail du produit anti-INPPL1 anticorps

Antigène: INPPL1 (Inositol Polyphosphate Phosphatase-Like 1 (INPPL1))

Épitope: AA 1172-1258

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp INPPL1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for INPPL1 detection. Tested with WB, IHC-P, Direct ELISA in Human,Mouse,Rat.

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for INPPL1 detection. Tested with WB, IHC-P, Direct ELISA in Human,Mouse,Rat.

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived human INPPL1 recombinant protein (Position: R1172-K1258).

Isotype: IgG

Information d'application

Indications d'application:

Application details: Western blot|0.1-0.5 μg/mL Immunohistochemistry(Paraffin-embedded Section)|0.5-1 μg/mL Direct ELISA|0.1-0.5 μg/mL

Commentaires:

Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur INPPL1

Antigène: INPPL1 (Inositol Polyphosphate Phosphatase-Like 1 (INPPL1))

Autre désignation: INPPL1 (INPPL1 Produits)

Synonymes: anticorps OPSMD, anticorps SHIP2, anticorps 51C, anticorps Ship2, anticorps inppl1, anticorps si:bz46j2.7, anticorps si:rp71-46j2.7, anticorps INPPL1, anticorps fc58a04, anticorps wu:fc58a04, anticorps zgc:198309, anticorps inositol polyphosphate phosphatase like 1, anticorps inositol polyphosphate phosphatase-like 1, anticorps inositol polyphosphate phosphatase-like 1b, anticorps phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2B, anticorps inositol polyphosphate phosphatase-like 1a, anticorps INPPL1, anticorps Inppl1, anticorps inppl1b, anticorps LOC100180571, anticorps inppl1a

Sujet:

Synonyms: Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2, Inositol polyphosphate phosphatase-like protein 1, INPPL-1, Protein 51C, SH2 domain-containing inositol 5'-phosphatase 2, SH2 domain-containing inositol phosphatase 2, SHIP-2, INPPL1, SHIP2

Background: SH2-domain containing Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2 is an enzyme that in humans is encoded by the INPPL1 gene. The protein encoded by this gene is an SH2-containing 5'-inositol phosphatase that is involved in the regulation of insulin function. The encoded protein also plays a role in the regulation of epidermal growth factor receptor turnover and actin remodelling. Additionally, this gene supports metastatic growth in breast cancer and is a valuable biomarker for breast cancer.

ID gène: 3636

UniProt: O15357

Pathways: Platelet-derived growth Factor Receptor Signaling