RRBP1 anticorps

N° du produit ABIN6719628

Détail du produit anti-RRBP1 anticorps

Antigène: RRBP1 (Ribosome Binding Protein 1 (RRBP1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RRBP1 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Fonction: Rabbit IgG polyclonal antibody for RRBP1 detection. Tested with WB, IHC-P, IHC-F, ICC, FCM in Human,Mouse,Rat.

Séquence: EKEKKLTSDL GRAATRLQEL LKTTQEQLAR EKDTVKKLQE QLEKAED

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for RRBP1 detection. Tested with WB, IHC-P, IHC-F, ICC, FCM in Human,Mouse,Rat.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence of human RRBP1(EKEKKLTSDLGRAATRLQELLKTTQEQLAREKDTVKKLQEQLEKAED).

Isotype: IgG

Information d'application

Indications d'application:

Application details: Western blot|0.1-0.5 μg/mL Immunohistochemistry(Paraffin-embedded Section)|0.5-1 μg/mL Immunohistochemistry(Frozen Section)|0.5-1 μg/mL Immunocytochemistry|0.5-1 μg/mL Flow Cytometry|1-3 μg/1x106 cells

Commentaires:

Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur RRBP1

Antigène: RRBP1 (Ribosome Binding Protein 1 (RRBP1))

Autre désignation: RRBP1 (RRBP1 Produits)

Synonymes: anticorps 1700087N07Rik, anticorps 5730465C04Rik, anticorps ES/130, anticorps mKIAA1398, anticorps mRRp0, anticorps mRRp1.8, anticorps mRRp10, anticorps mRRp15a, anticorps mRRp15b, anticorps mRRp16.8, anticorps mRRp2, anticorps mRRp41, anticorps mRRp47, anticorps mRRp5.4, anticorps p180, anticorps ES130, anticorps RRp, anticorps hES, anticorps P180, anticorps rrbp1, anticorps sb:cb489, anticorps wu:fc47a01, anticorps ribosome binding protein 1, anticorps ribosome binding protein 1 homolog 180kDa (dog), anticorps ribosome binding protein 1b, anticorps Rrbp1, anticorps RRBP1, anticorps rrbp1b

Sujet:

Synonyms: Ribosome-binding protein 1, 180 kDa ribosome receptor homolog, RRp, ES/130-related protein, Ribosome receptor protein, RRBP1, KIAA1398

Background: Ribosome-binding protein 1, also referred to as p180, is a protein that in humans is encoded by the RRBP1 gene. It is mapped to 20p12.1. This gene encodes a ribosome-binding protein of the endoplasmic reticulum (ER) membrane. Studies suggest that this gene plays a role in ER proliferation, secretory pathways and secretory cell differentiation, and mediation of ER-microtubule interactions. Alternative splicing has been observed and protein isoforms are characterized by regions of N-terminal decapeptide and C-terminal heptad repeats. Splicing of the tandem repeats results in variations in ribosome-binding affinity and secretory function. The full-length nature of variants which differ in repeat length has not been determined. Pseudogenes of this gene have been identified on chromosomes 3 and 7, and RRBP1 has been excluded as a candidate gene in the cause of Alagille syndrome, the result of a mutation in a nearby gene on chromosome 20p12.

ID gène: 6238

UniProt: Q9P2E9