Aggrecan anticorps (AA 101-220)

N° du produit ABIN673599

Cet anticorps anti-Aggrecan est un anticorps Lapin Polyclonal détectant Aggrecan dans WB, ELISA, IHC (p), IF (cc), IF (p) et IHC (fro). Adapté pour Humain, Rat, Souris et Lapin. Ce Primary Antibody a été cité dans 6+ publications.

Aperçu rapide pour Aggrecan anticorps (AA 101-220) (ABIN673599)

Antigène: Aggrecan (ACAN)

Reactivité: Humain, Rat, Souris, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Aggrecan est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-Aggrecan anticorps

Épitope: AA 101-220

Réactivité croisée: Humain, Souris, Lapin, Rat

Homologie: Dog,Cow,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Aggrecan core protein

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-Aggrecan (ABIN673599)

Hu, Yang, Chen, Sun, Lin, Yang: "Optimization of puncture injury to rat caudal disc for mimicking early degeneration of intervertebral disc." dans: Journal of orthopaedic research : official publication of the Orthopaedic Research Society, (2017) (PubMed).

Zhao, Hao, Wang, Wang: "Effect of Choline on the Composition and Degradation Enzyme of Extracellular Matrix of Mice Chondrocytes Exposed to Fluoride." dans: Biological trace element research, (2016) (PubMed).

Liu, Yu, Ma, Xiang, Hu, Chen: "Lentivirus-mediated TGF-β3, CTGF and TIMP1 gene transduction as a gene therapy for intervertebral disc degeneration in an in vivo rabbit model." dans: Experimental and therapeutic medicine, Vol. 11, Issue 4, pp. 1399-1404, (2016) (PubMed).

Shi, Ma, Zhang, Li, Jiang, Qin: "Hypoxia combined with spheroid culture improves cartilage specific function in chondrocytes." dans: Integrative biology : quantitative biosciences from nano to macro, (2015) (PubMed).

Lei, Li, Li, Gao, Chen, Jin: "Mesenchymal stem cell characteristics of dental pulp and periodontal ligament stem cells after in vivo transplantation." dans: Biomaterials, Vol. 35, Issue 24, pp. 6332-43, (2014) (PubMed).

Ren, Liu, Ma, Liu, Diao, Yang, Zhang, Xi, Hu: "Treatment of rabbit intervertebral disc degeneration with co-transfection by adeno-associated virus-mediated SOX9 and osteogenic protein-1 double genes in vivo." dans: International journal of molecular medicine, Vol. 32, Issue 5, pp. 1063-8, (2014) (PubMed).

Détails sur Aggrecan

Antigène: Aggrecan (ACAN)

Autre désignation: Aggrecan core protein 1

Sujet:

Synonyms: AGC1, SEDK, AGCAN, CSPG1, MSK16, CSPGCP, Aggrecan core protein, Cartilage-specific proteoglycan core protein, CSPCP, Chondroitin sulfate proteoglycan core protein 1, Chondroitin sulfate proteoglycan 1, ACAN

Background: This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region.

ID gène: 176

UniProt: P16112

Pathways: Glycosaminoglycan Metabolic Process, Dicarboxylic Acid Transport