Metabotropic Glutamate Receptor 5 anticorps (PE)
Aperçu rapide pour Metabotropic Glutamate Receptor 5 anticorps (PE) (ABIN673924)
Antigène
Voir toutes Metabotropic Glutamate Receptor 5 (GRM5) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Réactivité croisée
- Rat
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Homologie
- Human,Mouse,Dog,Sheep,Chicken
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic peptide derived from mouse GRM5
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Isotype
- IgG
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Indications d'application
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FCM(1:100-500)
Optimal working dilution should be determined by the investigator. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Date de péremption
- 12 months
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- Metabotropic Glutamate Receptor 5 (GRM5) (Glutamate Receptor, Metabotropic 5 (GRM5))
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Autre désignation
- mGluR5
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Sujet
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Synonyms: Glu5R, Gprc1e, mGluR5, mGluR5b, AI850523, 6430542K11Rik, Metabotropic glutamate receptor 5, Grm5
Background: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. Plays an important role in the regulation of synaptic plasticity and the modulation of the neural network activity (By similarity).
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Poids moléculaire
- 132kDa
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ID gène
- 108071
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UniProt
- Q3UVX5
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Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of long-term Neuronal Synaptic Plasticity
Antigène
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