Apoptosis Inhibitor 5 anticorps (AA 351-460)
Aperçu rapide pour Apoptosis Inhibitor 5 anticorps (AA 351-460) (ABIN673959)
Antigène
Voir toutes Apoptosis Inhibitor 5 (API5) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 351-460
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Réactivité croisée
- Souris
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Homologie
- Human,Rat,Dog,Cow,Pig,Horse,Guinea Pig
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic peptide derived from human API5
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Isotype
- IgG
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Indications d'application
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WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Date de péremption
- 12 months
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- Apoptosis Inhibitor 5 (API5)
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Autre désignation
- API5
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Sujet
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Synonyms: AAC11, AAC-11, Apoptosis inhibitor 5, API-5, Antiapoptosis clone 11 protein, Cell migration-inducing gene 8 protein, Fibroblast growth factor 2-interacting factor, FIF, Protein XAGL, API5, MIG8
Background: Antiapoptotic factor that may have a role in protein assembly. Negatively regulates ACIN1. By binding to ACIN1, it suppresses ACIN1 cleavage from CASP3 and ACIN1-mediated DNA fragmentation. Also known to efficiently suppress E2F1-induced apoptosis. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs.
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ID gène
- 8539
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UniProt
- Q9BZZ5
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Pathways
- Growth Factor Binding
Antigène
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