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SERPINC1 anticorps (C-Term)

Cet anticorps Lapin Polyclonal détecte spécifiquement SERPINC1 dans WB. Il présente une réactivité envers Humain, Souris, Chien, Cheval et Singe et a été mentionné dans 4+ publications.
N° du produit ABIN6746198

Aperçu rapide pour SERPINC1 anticorps (C-Term) (ABIN6746198)

Antigène

Voir toutes SERPINC1 Anticorps
SERPINC1 (Serpin Family C Member 1 (SERPINC1))

Reactivité

  • 89
  • 46
  • 24
  • 5
  • 5
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Humain, Souris, Chien, Cheval, Singe

Hôte

  • 86
  • 19
  • 6
  • 6
  • 1
Lapin

Clonalité

  • 92
  • 26
Polyclonal

Conjugué

  • 63
  • 17
  • 14
  • 4
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp SERPINC1 est non-conjugé

Application

  • 83
  • 47
  • 29
  • 26
  • 22
  • 18
  • 16
  • 13
  • 13
  • 9
  • 8
  • 8
  • 5
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
Western Blotting (WB)
  • Épitope

    • 15
    • 6
    • 6
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    Specificité

    Mouse SERPINC1 / Antithrombin-III

    Homologie

    Percent identity by BLAST analysis: Human, Mouse, Dog, Horse (100%) Rat, Bovine, Rabbit, Pig, Guinea pig (92%).

    Purification

    Immunoaffinity purified

    Immunogène

    Synthetic peptide from C-Terminus of mouse Serpinc1 (P32261, NP_543120). Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Galago, Marmoset, Mouse, Elephant, Dog, Horse, Opossum (100%), Rat, Sheep, Panda, Bovine, Bat, Rabbit, Pig, Guinea pig, Platypus (92%), Xenopus (84%), Turkey (83%).

    Type of Immunogen: Synthetic peptide
  • Indications d'application

    Approved: WB (1 μg/mL)

    Usage: Western Blot: Suggested dilution at 1 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.

    Commentaires

    Target Species of Antibody: Mouse

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Distilled water

    Concentration

    Lot specific

    Buffer

    Lyophilized from PBS with 2 % sucrose

    Conseil sur la manipulation

    Avoid repeat freeze-thaw cycles.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
    Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.
  • Cool, Normant, Shen, Chen, Pannell, Zhang, Loh: "Carboxypeptidase E is a regulated secretory pathway sorting receptor: genetic obliteration leads to endocrine disorders in Cpe(fat) mice." dans: Cell, Vol. 88, Issue 1, pp. 73-83, (1997) (PubMed).

    Shen, Loh: "Intracellular misrouting and abnormal secretion of adrenocorticotropin and growth hormone in cpefat mice associated with a carboxypeptidase E mutation." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, Issue 10, pp. 5314-9, (1997) (PubMed).

    Varlamov, Fricker: "The C-terminal region of carboxypeptidase E involved in membrane binding is distinct from the region involved with intracellular routing." dans: The Journal of biological chemistry, Vol. 271, Issue 11, pp. 6077-83, (1996) (PubMed).

    Manser, Fernandez, Loo, Goh, Monfries, Hall, Lim: "Human carboxypeptidase E. Isolation and characterization of the cDNA, sequence conservation, expression and processing in vitro." dans: The Biochemical journal, Vol. 267, Issue 2, pp. 517-25, (1990) (PubMed).

  • Antigène

    SERPINC1 (Serpin Family C Member 1 (SERPINC1))

    Autre désignation

    SERPINC1 / Antithrombin III

    Sujet

    Name/Gene ID: SERPINC1

    Synonyms: SERPINC1, Antithrombin III, Antithrombin-III, ATIII, AT3, Serpin C1, AT3D, THPH7

    ID gène

    462

    NCBI Accession

    NP_543120

    UniProt

    P01008
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