CCR7 anticorps (AA 25-59)

N° du produit ABIN674724

Cet anticorps anti-CCR7 est un anticorps Lapin Polyclonal détectant CCR7 dans FACS, WB, ELISA, ICC, IHC (p), IF (p), IF (cc) et IHC (fro). Adapté pour Humain, Souris, Rat et Mouton. Ce Primary Antibody a été cité dans 4+ publications.

Aperçu rapide pour CCR7 anticorps (AA 25-59) (ABIN674724)

Antigène: CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))

Reactivité: Humain, Souris, Rat, Mouton

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CCR7 est non-conjugé

Application: Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-CCR7 anticorps

Épitope: AA 25-59

Réactivité croisée: Humain, Souris, Rat, Mouton

Homologie: Dog

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from mouse CCR7

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-CCR7 (ABIN674724)

Goyoneche Linares, Diaz-Obregón, Granda Alacote, Castro Núñez, Castañeda Torrico, Murillo Carrasco, Liendo Liendo, Rufasto Goche, Arrunátegui Correa, de León Delgado: "Leukocyte Dysregulation and Biochemical Alterations in End-Stage Kidney Disease Patients Under Hemodialysis." dans: Diseases (Basel, Switzerland), Vol. 13, Issue 4, (2025) (PubMed).

Li, Sun, Li, Gao, Yu, Zhao, Li, Zhao: "High Expression of CCR7 Predicts Lymph Node Metastasis and Good Prognosis in Triple Negative Breast Cancer." dans: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 43, Issue 2, pp. 531-539, (2017) (PubMed).

Blomgran, Blomgran, Ernerudh, Aspenberg: "A possible link between loading, inflammation and healing: Immune cell populations during tendon healing in the rat." dans: Scientific reports, Vol. 6, pp. 29824, (2016) (PubMed).

Ge, Li, Jiang, You, Liu, Zhong, Huang, Xing: "Integration of nondegradable polystyrene and degradable gelatin in a core-sheath nanofibrous patch for pelvic reconstruction." dans: International journal of nanomedicine, Vol. 10, pp. 3193-201, (2015) (PubMed).

Détails sur CCR7

Antigène: CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))

Autre désignation: CCR7/CD197

Sujet:

Synonyms: EBI1, CCR-7, CD197, Ebi1h, Cdw197, Cmkbr7, CC-CKR-7, C-C chemokine receptor type 7, C-C CKR-7, Epstein-Barr virus-induced G-protein coupled receptor 1, EBV-induced G-protein coupled receptor 1, MIP-3 beta receptor, Ccr7

Background: CCR7 is a member of the G protein coupled receptor family (subfamily : chemokine). This receptor was identified as a gene induced by the Epstein Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. CCR7 has been reported to be expressed in blood, bone marrow, lymph node, and intestine. It is particularly expressed in lymphoid tissues and in activated B and T lymphocytes and has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. ESTs have been isolated from blood, embryo, lymph node, and thymus libraries.

ID gène: 12775

UniProt: P47774

Pathways: Regulation of Actin Filament Polymerization, Positive Regulation of Immune Effector Process