CCR7 anticorps (AA 25-59) (Cy3)

N° du produit ABIN674727

Cet anticorps anti-CCR7 est un anticorps Lapin Polyclonal détectant CCR7 dans FACS, WB, IF (p) et IF (cc). Adapté pour Humain, Souris, Rat et Mouton.

Aperçu rapide pour CCR7 anticorps (AA 25-59) (Cy3) (ABIN674727)

Antigène: CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))

Reactivité: Humain, Souris, Rat, Mouton

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CCR7 est conjugé à/à la Cy3

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Détail du produit anti-CCR7 anticorps (Cy3)

Épitope: AA 25-59

Réactivité croisée: Humain, Souris, Rat, Mouton

Homologie: Dog

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from mouse CCR7

Isotype: IgG

Information d'application

Indications d'application: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur CCR7

Antigène: CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))

Autre désignation: CCR7/CD197

Sujet:

Synonyms: EBI1, CCR-7, CD197, Ebi1h, Cdw197, Cmkbr7, CC-CKR-7, C-C chemokine receptor type 7, C-C CKR-7, Epstein-Barr virus-induced G-protein coupled receptor 1, EBV-induced G-protein coupled receptor 1, MIP-3 beta receptor, Ccr7

Background: CCR7 is a member of the G protein coupled receptor family (subfamily : chemokine). This receptor was identified as a gene induced by the Epstein Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. CCR7 has been reported to be expressed in blood, bone marrow, lymph node, and intestine. It is particularly expressed in lymphoid tissues and in activated B and T lymphocytes and has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. ESTs have been isolated from blood, embryo, lymph node, and thymus libraries.

ID gène: 12775

UniProt: P47774

Pathways: Regulation of Actin Filament Polymerization, Positive Regulation of Immune Effector Process