PDGF-BB Homodimer (AA 151-241) anticorps

N° du produit ABIN674874

Cet anticorps anti- est un anticorps Lapin Polyclonal détectant dans WB, ELISA, IF (cc), IF (p), IHC (p) et IHC (fro). Adapté pour Humain, Souris, Rat et Poulet. Ce Primary Antibody a été cité dans 1 publication.

Aperçu rapide pour PDGF-BB Homodimer (AA 151-241) anticorps (ABIN674874)

Antigène: PDGF-BB Homodimer

Reactivité: Humain, Souris, Rat, Poulet

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit

Épitope: AA 151-241

Réactivité croisée: Poulet, Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human PDGF-B

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Référence

Cipriani, Di Benedetto, Dietrich, Ruscitti, Liakouli, Carubbi, Pantano, Berardicurti, Sgonc, Giacomelli: "Searching for a good model for systemic sclerosis: the molecular profile and vascular changes occurring in UCD-200 chickens strongly resemble the early phase of human systemic sclerosis." dans: Archives of medical science : AMS, Vol. 12, Issue 4, pp. 828-43, (2016) (PubMed).

Détail du antigène

Antigène: PDGF-BB Homodimer

Autre désignation: PDGFBB

Sujet:

Synonyms: PDGF BB, PDGF-BB, platelet derived growth factor-BB, Becaplermin, C sis, FLJ12858, Oncogene SIS, PDG B chain, PDGB, PDGF 2, PDGF B, PDGF B chain, PDGF2, PDGFB, PDGFB/COL1A1 fusion gene, Platelet derived growth factor 2, Platelet derived growth factor B chain, Platelet derived growth factor beta, Platelet derived growth factor beta polypeptide, Simian sarcoma viral v sis oncogene homolog, SIS, SSV, V sis platelet derived growth factor beta polypeptide.

Background: Platelet Derived Growth Factor (PDGF) is the major serum mitogen for cells of mesenchymal origin in humans. The biologically active protein is a dimer composed of two related polypeptides designated A and B, the dimers being connected by disulfide bonds. The PDGF protein has been implicated both directly as well as indirectly in several pathological states including neoplasia, arthritis, arteriosclerosis and bone marrow sclerosis.

ID gène: 5155