MITF anticorps (AA 351-450)

N° du produit ABIN676373

L’anticorps Lapin Polyclonal anti-MITF a été validé pour WB, ELISA, IHC (p) et IF (p). Il convient pour détecter MITF dans des échantillons de Souris. Il y a 4+ publications disponibles.

Aperçu rapide pour MITF anticorps (AA 351-450) (ABIN676373)

Antigène: MITF (Microphthalmia-Associated Transcription Factor (MITF))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MITF est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-MITF anticorps

Épitope: AA 351-450

Réactivité croisée: Souris

Homologie: Human,Rat,Dog,Cow,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human MITF

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-MITF (ABIN676373)

Rice, Cebra-Thomas, Haugas, Partanen, Rice, Gilbert: "Melanoblast development coincides with the late emerging cells from the dorsal neural tube in turtle Trachemys scripta." dans: Scientific reports, Vol. 7, Issue 1, pp. 12063, (2019) (PubMed).

Kito, Saigo, Takeuchi: "Novel Transgenic Mouse Model of Polycystic Kidney Disease." dans: The American journal of pathology, Vol. 187, Issue 9, pp. 1916-1922, (2017) (PubMed).

Han, Sung, Lee: "Antimelanogenesis Activity of Hydrolyzed Ginseng Extract (GINST) via Inhibition of JNK Mitogen-activated Protein Kinase in B16F10 Cells." dans: Journal of food science, Vol. 81, Issue 8, pp. H2085-92, (2016) (PubMed).

Détails sur MITF

Antigène: MITF (Microphthalmia-Associated Transcription Factor (MITF))

Autre désignation: Mitf

Sujet:

Synonyms: MI, WS2, CMM8, WS2A, bHLHe32, Microphthalmia-associated transcription factor, Class E basic helix-loop-helix protein 32, MITF

Background: Transcription factor that regulates the expression of genes with essential roles in cell differentiation, proliferation and survival. Binds to symmetrical DNA sequences (E-boxes) (5'-CACGTG-3') found in the promoters of target genes, such as BCL2 and tyrosinase (TYR). Plays an important role in melanocyte development by regulating the expression of tyrosinase (TYR) and tyrosinase-related protein 1 (TYRP1). Plays a critical role in the differentiation of various cell types, such as neural crest-derived melanocytes, mast cells, osteoclasts and optic cup-derived retinal pigment epithelium.

ID gène: 4286

UniProt: O75030

Pathways: Chromatin Binding