ARHGAP17 anticorps (AA 451-550)

N° du produit ABIN679343

L’anticorps Lapin Polyclonal anti-ARHGAP17 a été validé pour ELISA, IHC (p), IF (cc), IF (p) et IHC (fro). Il convient pour détecter ARHGAP17 dans des échantillons de Rat.

Aperçu rapide pour ARHGAP17 anticorps (AA 451-550) (ABIN679343)

Antigène: ARHGAP17 (rho GTPase Activating Protein 17 (ARHGAP17))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARHGAP17 est non-conjugé

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-ARHGAP17 anticorps

Épitope: AA 451-550

Réactivité croisée: Rat

Homologie: Human,Mouse,Drosophila

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from fruit fly ARHGAP17/Nadrin

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur ARHGAP17

Antigène: ARHGAP17 (rho GTPase Activating Protein 17 (ARHGAP17))

Autre désignation: ARHGAP17

Sujet:

Synonyms: ARHGAP17, NADRIN, Neuron associated developmentally regulated protein, Rho GTPase activating protein 17, RhoGAP interacting with CIP4 homologs protein 1, RICH 1, RICH1, WBP15, MST066, MST110, MSTP038, PP367, PP4534, Rho type GTPase activating protein 17, RhoGAP interacting with CIP4 homologs 1, RICH1B.

Background: ARHGAP17 is a Rho GTPase-activating protein involved in the maintenance of tight junction by regulating the activity of CDC42, thereby playing a central role in apical polarity of epithelial cells. It specifically acts as a GTPase activator for the CDC42 GTPase by converting it to an inactive GDP-bound state. The complex formed with AMOT acts by regulating the uptake of polarity proteins at tight junctions, possibly by deciding whether tight junction transmembrane proteins are recycled back to the plasma membrane or sent elsewhere. RHGAP17 participates in the Ca(2+)-dependent regulation of exocytosis, possibly by catalyzing GTPase activity of Rho family proteins and by inducing the reorganization of the cortical actin filaments. Acts as a GTPase activator in vitro for RAC1.

ID gène: 55114