MAP3K11 anticorps (AA 355-460) (Cy3)

N° du produit ABIN682576

Cet anticorps Lapin Polyclonal détecte spécifiquement MAP3K11 dans WB, IF (cc) et IF (p). Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour MAP3K11 anticorps (AA 355-460) (Cy3) (ABIN682576)

Antigène: MAP3K11 (Mitogen-Activated Protein Kinase Kinase Kinase 11 (MAP3K11))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAP3K11 est conjugé à/à la Cy3

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-MAP3K11 anticorps (Cy3)

Épitope: AA 355-460

Specificité: Due to the similarity of this protein to MLK1 2 and 4, there is a chance that this antibody will cross-react based on homology.

Réactivité croisée: Humain, Souris, Rat

Homologie: Cow,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human MLK3

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur MAP3K11

Antigène: MAP3K11 (Mitogen-Activated Protein Kinase Kinase Kinase 11 (MAP3K11))

Autre désignation: MLK3

Sujet:

Synonyms: MLK3, PTK1, SPRK, MLK-3, MEKK11, Mitogen-activated protein kinase kinase kinase 11, Mixed lineage kinase 3, Src-homology 3 domain-containing proline-rich kinase, MAP3K11

Background: Activates the JUN N-terminal pathway. Required for serum-stimulated cell proliferation and for mitogen and cytokine activation of MAPK14 (p38), MAPK3 (ERK) and MAPK8 (JNK1) through phosphorylation and activation of MAP2K4/MKK4 and MAP2K7/MKK7. Plays a role in mitogen-stimulated phosphorylation and activation of BRAF, but does not phosphorylate BRAF directly. Influences microtubule organization during the cell cycle.

Poids moléculaire: 94kDa

ID gène: 4296

UniProt: Q16584

Pathways: Signalisation MAPK, Interferon-gamma Pathway