MAP3K11 anticorps (AA 355-460) (FITC)

N° du produit ABIN682580

L’anticorps anti-MAP3K11 Polyclonal Lapin est utilisé pour la détection de MAP3K11 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, IF (cc) et IF (p).

Aperçu rapide pour MAP3K11 anticorps (AA 355-460) (FITC) (ABIN682580)

Antigène: MAP3K11 (Mitogen-Activated Protein Kinase Kinase Kinase 11 (MAP3K11))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAP3K11 est conjugé à/à la FITC

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-MAP3K11 anticorps (FITC)

Épitope: AA 355-460

Specificité: Due to the similarity of this protein to MLK1 2 and 4, there is a chance that this antibody will cross-react based on homology.

Réactivité croisée: Humain, Souris, Rat

Homologie: Cow,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human MLK3

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur MAP3K11

Antigène: MAP3K11 (Mitogen-Activated Protein Kinase Kinase Kinase 11 (MAP3K11))

Autre désignation: MLK3

Sujet:

Synonyms: MLK3, PTK1, SPRK, MLK-3, MEKK11, Mitogen-activated protein kinase kinase kinase 11, Mixed lineage kinase 3, Src-homology 3 domain-containing proline-rich kinase, MAP3K11

Background: Activates the JUN N-terminal pathway. Required for serum-stimulated cell proliferation and for mitogen and cytokine activation of MAPK14 (p38), MAPK3 (ERK) and MAPK8 (JNK1) through phosphorylation and activation of MAP2K4/MKK4 and MAP2K7/MKK7. Plays a role in mitogen-stimulated phosphorylation and activation of BRAF, but does not phosphorylate BRAF directly. Influences microtubule organization during the cell cycle.

Poids moléculaire: 94kDa

ID gène: 4296

UniProt: Q16584

Pathways: Signalisation MAPK, Interferon-gamma Pathway