BMI1 anticorps (AA 61-160)
Aperçu rapide pour BMI1 anticorps (AA 61-160) (ABIN682678)
Antigène
Voir toutes BMI1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 61-160
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Réactivité croisée
- Humain
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Homologie
- Mouse,Rat,Dog,Cow,Chicken,Rabbit
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic peptide derived from human Bmi1/PCGF4
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Isotype
- IgG
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Indications d'application
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WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Date de péremption
- 12 months
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- BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))
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Autre désignation
- BMI1
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Sujet
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Synonyms: PCGF4, RNF51, FLVI2/BMI1, Polycomb complex protein BMI-1, Polycomb group RING finger protein 4, RING finger protein 51, BMI1
Background: Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.
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ID gène
- 648
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UniProt
- P35226
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Pathways
- Cycle Cellulaire, Autophagy
Antigène
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