Ephrin B1 anticorps (pSer300) (Biotin)

N° du produit ABIN684540

Cet anticorps anti-Ephrin B1 est un anticorps Lapin Polyclonal détectant Ephrin B1 dans WB et IHC (p). Adapté pour Humain, Souris, Rat, Poulet, Boeuf (Vache), Chien et Porc.

Aperçu rapide pour Ephrin B1 anticorps (pSer300) (Biotin) (ABIN684540)

Antigène: Ephrin B1 (EFNB1)

Reactivité: Humain, Souris, Rat, Poulet, Boeuf (Vache), Chien, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Ephrin B1 est conjugé à/à la Biotin

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-Ephrin B1 anticorps (Biotin)

Épitope: pSer300

Réactivité croisée: Boeuf (Vache), Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human Ephrin B around the phosphorylation site of Ser300

Isotype: IgG

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur Ephrin B1

Antigène: Ephrin B1 (EFNB1)

Autre désignation: EFNB1

Sujet:

Synonyms: Ephrin B phospho Y330, p-Ephrin B phospho Y330, CEK5 ligand, EFNB1, ELK L, EphrinB, Ephrin-B, ELK ligand, ELKL, EPH related receptor tyrosine kinase ligand 2, Ephrin B Precursor, Ephrin B1, Ephrin B2, LERK 2, LERK2, EFNB2_HUMAN.

Background: Ephrin B proteins are thought to play key roles in cellular functions as diverse as neuronal migration and blood vessel development. Ephrin B molecules expressed at the membrane surface bind to the Ephrin B family receptors on target cells during cell to cell contact. This interaction leads to cell signaling in the target cell but also generates a reverse signal in the cell expressing Ephrin B on its surface. This reverse signaling event is thought to be critical for vessel maturation and neuronal development. Importantly, tyrosine phosphorylation of Ephrin B is thought to be a critical component of this reverse signaling event. Recent work demonstrated that Tyr331 of Ephrin B was phosphorylated in HEK293 cells after stimulation by the soluble Ephrin B2 receptor tyrosine kinase.

Poids moléculaire: 38kDa

ID gène: 1947

Pathways: Signalisation RTK