GCN2 anticorps (pThr899)

N° du produit ABIN684943

Détail du produit anti-GCN2 anticorps

Antigène: GCN2 (EIF2AK4) (Eukaryotic Translation Initiation Factor 2 alpha Kinase 4 (EIF2AK4))

Épitope: pThr899

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GCN2 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Specificité: This phosphorylation site is homologous to Thr898 in Mouse and Thr899 in Rat.

Réactivité croisée: Humain

Homologie: Mouse,Rat,Dog,Cow,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human GCN2 around the phosphorylation site of Thr899

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-GCN2 (ABIN684943)

Lehman, Ryeom, Koumenis: "Signaling through alternative Integrated Stress Response pathways compensates for GCN2 loss in a mouse model of soft tissue sarcoma." dans: Scientific reports, Vol. 5, pp. 11781, (2015) (PubMed).

Détails sur GCN2

Antigène: GCN2 (EIF2AK4) (Eukaryotic Translation Initiation Factor 2 alpha Kinase 4 (EIF2AK4))

Autre désignation: GCN2 (EIF2AK4 Produits)

Synonymes: anticorps EIF2AK4, anticorps Gcn2-like, anticorps GCN2, anticorps 2610011M03, anticorps MGCN2, anticorps eukaryotic translation initiation factor 2 alpha kinase 4, anticorps eukaryotic translation initiation factor 2-alpha kinase 4, anticorps eIF-2-alpha kinase GCN2, anticorps EIF2AK4, anticorps LOC579979, anticorps LOC100187226, anticorps eif2ak4, anticorps Eif2ak4

Sujet:

Synonyms: GCN2, PVOD2, Eukaryotic translation initiation factor 2-alpha kinase 4, GCN2-like protein, EIF2AK4, KIAA1338

Background: GCN2 belongs to a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor 2 to downregulate protein synthesis in response to varied cellular stresses.

ID gène: 440275

UniProt: Q9P2K8

Pathways: ER-Nucleus Signaling, Hepatitis C