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ERK1/2 anticorps (pThr183, pTyr185) (Cy5)

L’anticorps Lapin Polyclonal anti-ERK1/2 a été validé pour WB, IF (cc) et IF (p). Il convient pour détecter ERK1/2 dans des échantillons de Humain, Souris et Rat.
N° du produit ABIN687731

Aperçu rapide pour ERK1/2 anticorps (pThr183, pTyr185) (Cy5) (ABIN687731)

Antigène

Voir toutes ERK1/2 (MAPK1/3) Anticorps
ERK1/2 (MAPK1/3) (Mitogen-Activated Protein Kinase 1/3 (MAPK1/3))

Reactivité

  • 180
  • 157
  • 153
  • 21
  • 21
  • 18
  • 6
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Humain, Souris, Rat

Hôte

  • 136
  • 47
  • 4
Lapin

Clonalité

  • 131
  • 56
Polyclonal

Conjugué

  • 81
  • 9
  • 6
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
Cet anticorp ERK1/2 est conjugé à/à la Cy5

Application

  • 135
  • 65
  • 50
  • 50
  • 40
  • 33
  • 25
  • 23
  • 18
  • 13
  • 6
  • 5
  • 4
  • 3
  • 1
Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • Épitope

    • 56
    • 37
    • 29
    • 29
    • 16
    • 12
    • 12
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pThr183, pTyr185

     Réactivité croisée

    Humain, Souris, Rat

    Homologie

    Dog,Cow,Pig,Horse,Chicken,Rabbit,Guinea Pig

    Purification

    Purified by Protein A.

    Immunogène

    KLH conjugated synthetic phosphopeptide derived from mouse ERK2 around the phosphorylation site of Thr183 and Tyr 185

    Isotype

    IgG
  • Indications d'application

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Agent conservateur

    ProClin

    Précaution d'utilisation

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Stock

    -20 °C

    Stockage commentaire

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Date de péremption

    12 months
  • Antigène

    ERK1/2 (MAPK1/3) (Mitogen-Activated Protein Kinase 1/3 (MAPK1/3))

    Autre désignation

    ERK1, ERK2

    Sub Type

    Cocktail

    Sujet

    Synonyms: ERK, Erk2, MAPK2, PRKM2, Prkm1, C78273, p41mapk, p42mapk, AA47128, AU18647, 93612K14Rik, Mitogen-activated protein kinase 1, MAP kinase 1, MAPK 1, ERT1, Extracellular signal-regulated kinase 2, ERK-2, MAP kinase isoform p42, p42-MAPK, Mitogen-activated protein kinase 2, MAP kinase 2, MAPK 2, Mapk1, Mapk

    Background: Acts as a transcriptional repressor. Binds to a [GC]AAA[GC] consensus sequence. Repress the expression of interferon gamma-induced genes. Seems to bind to the promoter of CCL5, DMP1, IFIH1, IFITM1, IRF7, IRF9, LAMP3, OAS1, OAS2, OAS3 and STAT1. Transcriptional activity is independent of kinase activity (By similarity).

    ID gène

    26413

    UniProt

    P63085
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