ERK1/2 anticorps (pThr183, pTyr185) (Cy5)
Aperçu rapide pour ERK1/2 anticorps (pThr183, pTyr185) (Cy5) (ABIN687731)
Antigène
Voir toutes ERK1/2 (MAPK1/3) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- pThr183, pTyr185
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Réactivité croisée
- Humain, Souris, Rat
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Homologie
- Dog,Cow,Pig,Horse,Chicken,Rabbit,Guinea Pig
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic phosphopeptide derived from mouse ERK2 around the phosphorylation site of Thr183 and Tyr 185
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Isotype
- IgG
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Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Date de péremption
- 12 months
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- ERK1/2 (MAPK1/3) (Mitogen-Activated Protein Kinase 1/3 (MAPK1/3))
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Autre désignation
- ERK1, ERK2
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Sub Type
- Cocktail
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Sujet
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Synonyms: ERK, Erk2, MAPK2, PRKM2, Prkm1, C78273, p41mapk, p42mapk, AA47128, AU18647, 93612K14Rik, Mitogen-activated protein kinase 1, MAP kinase 1, MAPK 1, ERT1, Extracellular signal-regulated kinase 2, ERK-2, MAP kinase isoform p42, p42-MAPK, Mitogen-activated protein kinase 2, MAP kinase 2, MAPK 2, Mapk1, Mapk
Background: Acts as a transcriptional repressor. Binds to a [GC]AAA[GC] consensus sequence. Repress the expression of interferon gamma-induced genes. Seems to bind to the promoter of CCL5, DMP1, IFIH1, IFITM1, IRF7, IRF9, LAMP3, OAS1, OAS2, OAS3 and STAT1. Transcriptional activity is independent of kinase activity (By similarity).
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ID gène
- 26413
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UniProt
- P63085
Antigène
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