tau anticorps (pSer202, pThr205) (Atto 594)
Aperçu rapide pour tau anticorps (pSer202, pThr205) (Atto 594) (ABIN6932888)
Antigène
Voir toutes tau AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- pSer202, pThr205
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Specificité
- Expressed in neurons.,Detects ~79 kDa.
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Réactivité croisée
- Humain, Souris
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Purification
- Affinity Purified
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Immunogène
- Synthetic peptide of Human Phospho Tau (Ser202/Thr205)
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Isotype
- IgG
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Indications d'application
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- WB (1:500)
- ICC/IF (1:500)
- IHC (1:500)
- optimal dilutions for assays should be determined by the user.
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Commentaires
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A 1:500 dilution of ABIN6932888 was sufficient for detection of Tau in 10 μg Baculovirus by dot blot analysis using Goat Anti-Rabbit IgG:HRP as the secondary antibody.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS pH 7.4, 50 % glycerol, 0.09 % Sodium azide, Storage buffer may change when conjugated
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- Conjugated antibodies should be stored at 4°C
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- tau (tau Protein)
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Autre désignation
- Tau
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Sujet
- Alzheimer's Disease (AD) is the most common neurodegenerative disease, affecting 10 % of seniors over the age of 65 (1). It was named after Alois Alzheimer, a German scientist who discovered tangled bundles of fibrils where neurons had once been in the brain of a deceased patient in 1907 (2). Tau (tubulin-associated unit) is normally located in the axons of neurons where it stabilizes microtubules. Tauopathies such as AD are characterized by neurofibrillary tangles containing hyperphosphorylated tau fibrils (3).
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ID gène
- 4137
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UniProt
- P10636
Antigène
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