Chromogranin A anticorps (CF®488A)
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- Antigène Voir toutes Chromogranin A (CHGA) Anticorps
- Chromogranin A (CHGA)
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp Chromogranin A est conjugé à/à la CF®488A
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Application
- Immunofluorescence (IF), Flow Cytometry (FACS), Test (T)
- Specificité
- Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.
- Réactivité croisée (Details)
- Human,
- Purification
- Antibody Purified from Bioreactor Concentrate by Protein A/G and conjugated to various reporter molecules.
- Immunogène
- Recombinant human chromogranin A protein
- Clone
- CGA-414
- Isotype
- IgG1
- Top Product
- Discover our top product CHGA Anticorps primaire
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- Indications d'application
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Positive Control: PC12 cells. Adrenal gland, bowel, thyroid, pancreas or pheochromocytoma.
Known Application: Flow Cytometry (5 µL per test per one million cells or 5 µL per 100 µL of whole blood),Immunofluorescence (1:50-1:100),Optimal dilution for a specific application should be determined.
- Restrictions
- For Research Use only
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- Concentration
- 100 μg/mL
- Buffer
- Prepared in 10 mM PBS with 0.05 % BSA and 0.05 % azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Stockage commentaire
- Antibody with azide - store at 2 to 8 °C. Antibody is stable for 24 months. Non-hazardous. Also available WITHOUT BSA & azide at 1.0mg/ml.
- Date de péremption
- 24 months
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- Antigène
- Chromogranin A (CHGA)
- Autre désignation
- CHGA (CHGA Produits)
- Synonymes
- anticorps CGA, anticorps CG-ALPHA, anticorps FSHA, anticorps GPHA1, anticorps GPHa, anticorps HCG, anticorps LHA, anticorps TSHA, anticorps ChrA, anticorps fj05f09, anticorps si:dkey-177p2.2, anticorps wu:fj05f09, anticorps zgc:101749, anticorps zgc:56075, anticorps CHGA, anticorps cgA, anticorps chga, anticorps chromogranin A, anticorps glycoprotein hormones, alpha polypeptide, anticorps uncharacterized CHGA, anticorps chromogranin A S homeolog, anticorps CHGA, anticorps CGA, anticorps Chga, anticorps chga, anticorps chga.S
- Sujet
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Beta-Granin, CGA, CHGA, Chromogranin A Parathyroid Secretory Protein 1, ER-37, Pancreastatin, Parastatin, Parathyroid Secretory Protein 1, Pituitary Secretory Protein I, SP-I, Vasostatin I or II,Chromogranin A / CHGA (Neuroendocrine Marker)
Cellular localisation: Finely granular cytoplasmic - Poids moléculaire
- 68-75kDa
- ID gène
- 1113, 150793
- UniProt
- P10645
- Pathways
- Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling
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