Estrogen Receptor alpha anticorps (AA 2-185) (CF®488A)

N° du produit ABIN6935634

L’anticorps anti-Estrogen Receptor alpha Monoclonal Souris est utilisé pour la détection de Estrogen Receptor alpha dans des échantillons de Humain. Il a été validé pour IF et FACS.

Aperçu rapide pour Estrogen Receptor alpha anticorps (AA 2-185) (CF®488A) (ABIN6935634)

Antigène: Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Estrogen Receptor alpha est conjugé à/à la CF®488A

Application: Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: ER506

Détail du produit anti-Estrogen Receptor alpha anticorps (CF®488A)

Épitope: AA 2-185

Specificité: This MAb is specific to ER alpha and shows minimal cross-reaction with other members of the family. ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy. It strongly stains nuclei of epithelial cells in breast carcinomas.

Purification: Purified by Protein A/G

Immunogène: Recombinant human Estrogen Receptor alpha protein (aa2-185)

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Positive Control: MCF-7 cells. Breast or Endometrial Carcinoma.

Known Application: Flow Cytometry (5 µL per test per one million cells or 5 µL per 100 µL of whole blood),Immunofluorescence (1:50-1:100),Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 100 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA and 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 4 to 8°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur Estrogen Receptor alpha

Antigène: Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))

Autre désignation: ESR1

Poids moléculaire: ~67kDa

ID gène: 2099

UniProt: P03372

Pathways: Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly