CD34 anticorps (PE)

N° du produit ABIN6935798

Cet anticorps Souris Monoclonal détecte spécifiquement CD34 dans FACS, IF et T. Il présente une réactivité envers Humain et Rat.

Aperçu rapide pour CD34 anticorps (PE) (ABIN6935798)

Antigène: CD34

Reactivité: Humain, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD34 est conjugé à/à la PE

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Test (T)

Clone: ICO-115

Détail du produit anti-CD34 anticorps (PE)

Specificité: This antibody recognizes a carbohydrate epitope on a single chain, transmembrane, heavily glycosylated protein of 90-120 kDa, which is identified as CD34 (VI international workshop on human differentiation antigens). Its expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, it is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. CD34 expression is also found in vascular endothelium. Additionally, it appears that proliferating endothelial cells overexpress this molecule than the non-proliferating endothelial cells. Anti-CD34 labels 85 % of angiosarcoma and Kaposi's sarcoma, but shows low specificity.

Purification: Purified by Protein A/G

Immunogène: Blast cells of a chronic myeloid leukemia patient

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Positive Control: KG-1 cells. Human tonsil or angiosarcoma.

Known Application: Flow Cytometry: 5 µL per test per one million cells (or 5 µL per 100 µL of whole blood)Immunofluorescence (1:50-1:100)Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 100 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA and 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 4 to 8°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur CD34

Antigène: CD34

Autre désignation: CD34

Poids moléculaire: 90-110kDa

ID gène: 947

UniProt: P28906