Iba1 anticorps (AA 1-146)

N° du produit ABIN6936370

Cet anticorps anti-Iba1 Monoclonal Souris (Clone AIF1-1909) (ABIN6936370) détecte spécifiquement Iba1 dans IHC. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Iba1 anticorps (AA 1-146) (ABIN6936370)

Antigène: Iba1 (IBA1) (Ionized Calcium-binding Adapter Molecule 1 (IBA1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Iba1 est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: AIF1-1909

Détail du produit anti-Iba1 anticorps

Épitope: AA 1-146

Fonction: AIF1 / Iba1 (Microglia Marker) Antibody

Specificité: AIF1 is a cytoplasmic, calcium-binding protein that is thought to play a role in macrophage activation and function. AIF1, containing two EF domains, is induced by cytokines and Interferons. In an unstimulated state, AIF1 colocalizes with actin, and upon stimulation, translocates to lamellipodia. It is also a marker of human microglia and is expressed by macrophages in injured skeletal muscle. The gene encoding AIF1 resides in the tumor necrosis factor (TNF) cluster of genes, located in the region represented by the human major histocompatibility complex (MHC).

Réactivité croisée (Details): Human.

Purification: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Purified fragment of human recombinant AIF1 protein (around aa 1-146) (exact sequence is proprietary)

Isotype: IgG1, kappa

Information d'application

Indications d'application:

Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

Positive_Control: Lymph Node, Tonsil or Kidney.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur Iba1

Antigène: Iba1 (IBA1) (Ionized Calcium-binding Adapter Molecule 1 (IBA1))

Autre désignation: AIF1

Sujet:

Allograft inflammatory factor 1 (AIF1), balloon angioplasty responsive transcription (BART1), IBA1, Interferon responsive transcript 1, Ionized calcium-binding adapter molecule 1, IRT1, Microglia response factor (MRF1)

Human lymph node, tonsil or kidney.

Poids moléculaire: 17kDa

ID gène: 199, 76364

UniProt: P55008

Pathways: Smooth Muscle Cell Migration