AKR1C2 anticorps
Aperçu rapide pour AKR1C2 anticorps (ABIN6936375)
Antigène
Voir toutes AKR1C2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- DDH2 / AKR1C2 is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone.
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Réactivité croisée (Details)
- Human.
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Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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Immunogène
- Recombinant human full-length AKR1C2 protein
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Isotype
- IgG2a kappa
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Indications d'application
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Known_Application: Western Blot (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: HeLa, K-562, A431, HepG2, A549 cells. Human liver or stomach tissue.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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Agent conservateur
- Azide free
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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Date de péremption
- 24 months
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- AKR1C2 (Aldo-keto Reductase Family 1, Member C2 (AKR1C2))
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Autre désignation
- AKR1C2
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Sujet
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AKR1C2, 3-alpha-HSD3, AKR1C-pseudo protein, BABP, Dihydrodiol dehydrogenase 2, DD-2, MCDR2, HAKRD, DD, DDH2, HBAB, Pseudo-chlordecone reductase, SRXY8,Aldo-keto Reductase Family 1 Member C2 / DD2
Cellular localisation: Cytoplasm. -
Poids moléculaire
- 37kDa
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ID gène
- 1646, 567256
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UniProt
- P52895
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Pathways
- Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process
Antigène
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