CD147 anticorps

N° du produit ABIN6936531

L’anticorps Souris Monoclonal anti-CD147 a été validé pour FACS et IF. Il convient pour détecter CD147 dans des échantillons de Humain.

Aperçu rapide pour CD147 anticorps (ABIN6936531)

Antigène: CD147 (BSG) (Basigin (Ok Blood Group) (BSG))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD147 est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: CB43

Détail du produit anti-CD147 anticorps

Specificité: CD147 is a transmembrane glycoprotein of the immunoglobulin superfamily. It is expressed more intensely on thymocytes than on mature peripheral blood T cells. CD147 is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. CD147 is involved in the regulation of matrix remodeling at the epidermal-dermal interface. It stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes, which are typically increased during tissue degradation and wound healing, are important factors in cancer invasion and metastasis.

Réactivité croisée (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Native human leucocytes

Isotype: IgM kappa

Information d'application

Indications d'application:

Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.

Positive_Control: HSB2 cells. Renal Cell, Ovarian carcinoma or Melanoma.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Purified Ab WITHOUT BSA at 1.0mg/ml

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur CD147

Antigène: CD147 (BSG) (Basigin (Ok Blood Group) (BSG))

Autre désignation: BSG

Sujet: 5A11 Antigen, 5F7, Basigin, Blood brain barrier HT7 antigen BSG, Emmprin, Extracellular Matrix Metalloproteinase Inducer, Leukocyte Activation Antigen M6, Neurothelin, OK Blood Group Antigen, TCSF, Tumor Cell-derived Collagenase Stimulatory Factor,CD147 / EMMPRIN / Neurothelin
Cellular localisation: Cell surface

Poids moléculaire: 35kDa (non-reduced), 40kDa (reduced)

ID gène: 682, 501293

UniProt: P35613

Pathways: S100 Proteins