CD147 anticorps

N° du produit ABIN6936532

Détail du produit anti-CD147 anticorps

Antigène: CD147 (BSG) (Basigin (Ok Blood Group) (BSG))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD147 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Aggregation (AGG)

Specificité: This MAb recognizes extracellular epitope 2 within the N-terminal Ig domain of human CD147. It is expressed more intensely on thymocytes than on mature peripheral blood T cells. CD147 is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. It stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes are important factors in cancer invasion and metastasis.

Réactivité croisée (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Human T cell line Molt 13

Clone: 8D6

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Known_Application: Inhibits Homotypic Aggregation, Adhesion to Matrix Proteins, & Migation through Matrigel (Order w/o BSA / azide),Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (1-2 μg/mL), ,Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Positive_Control: HSB2 cells. Human renal cell carcinoma, ovarian carcinoma or melanoma.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur CD147

Antigène: CD147 (BSG) (Basigin (Ok Blood Group) (BSG))

Autre désignation: BSG (BSG Produits)

Synonymes: anticorps EMMPRIN, anticorps RPE7, anticorps 5F7, anticorps CD147, anticorps M6, anticorps OK, anticorps TCSF, anticorps AI115436, anticorps AI325119, anticorps HT-7, anticorps 5A11, anticorps CE9, anticorps HT7, anticorps Ox47R, anticorps basignin, anticorps wu:fb26a05, anticorps wu:fo98e12, anticorps bsg, anticorps prso03, anticorps basigin (Ok blood group), anticorps basigin, anticorps basigin (Ok blood group) S homeolog, anticorps BSG, anticorps Bsg, anticorps bsg, anticorps bsg.S

Sujet: 5A11 Antigen, 5F7, Basigin, Blood brain barrier HT7 antigen BSG, Extracellular Matrix Metalloproteinase Inducer (EMMPRIN), Leukocyte Activation Antigen M6, Neurothelin, OK Blood Group Antigen, TCSF, Tumor Cell-derived Collagenase Stimulatory Factor,CD147 / EMMPRIN / Neurothelin
Cellular localisation: Cell surface

Poids moléculaire: 35kDa (non-reduced), 40kDa (reduced)

ID gène: 682, 501293

UniProt: P35613

Pathways: S100 Proteins