Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

CA8 anticorps

CA8 Reactivité: Humain WB, IHC (f) Hôte: Souris Monoclonal CPTC-CA8-2 unconjugated
N° du produit ABIN6936553
  • Antigène Voir toutes CA8 Anticorps
    CA8 (Carbonic Anhydrase VIII (CA8))
    Reactivité
    • 46
    • 18
    • 15
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    Humain
    Hôte
    • 42
    • 4
    Souris
    Clonalité
    • 43
    • 3
    Monoclonal
    Conjugué
    • 20
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CA8 est non-conjugé
    Application
    • 15
    • 13
    • 13
    • 12
    • 11
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    Specificité
    The protein encoded by this gene was initially named CA-related protein because of sequence similarity to other known carbonic anhydrase genes. However, the gene product lacks carbonic anhydrase activity (i.e., the reversible hydration of carbon dioxide). The gene product continues to carry a carbonic anhydrase designation based on clear sequence identity to other members of the carbonic anhydrase gene family. The absence of CA8 gene transcription in the cerebellum of the lurcher mutant in mice with a neurologic defect suggests an important role for this acatalytic form. Mutations in CA8 gene causes neuropathology, such as ataxia, mild mental retardation and the predisposition to quadrupedal gait. It is also associated with the development of colorectal and lung cancers. Additionally, it is upregulated in various cancers.
    Réactivité croisée (Details)
    Human.
    Purification
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    Immunogène
    Recombinant full-length human CA8 protein
    Clone
    CPTC-CA8-2
    Isotype
    IgG2a kappa
    Top Product
    Discover our top product CA8 Anticorps primaire
  • Indications d'application

    Known_Application: Western Blot (1-2 μg/mL), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Positive_Control: Human cerebellum. Selective expression in purkinje cells. HEK-293 or K-562 cell lines.

    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    Agent conservateur
    Azide free
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    Date de péremption
    24 months
  • Antigène
    CA8 (Carbonic Anhydrase VIII (CA8))
    Autre désignation
    CA8 (CA8 Produits)
    Synonymes
    anticorps AW546993, anticorps Ca8, anticorps Cals, anticorps Cals1, anticorps Carp, anticorps wdl, anticorps zgc:110118, anticorps CA-VIII, anticorps CALS, anticorps CAMRQ3, anticorps CARP, anticorps carbonic anhydrase 8, anticorps carbonic anhydrase VIII, anticorps CAH8, anticorps Car8, anticorps ca8, anticorps CA8
    Sujet
    CA-VIII, CALS, CARP, MGC120502, MGC99509,Carbonic Anhydrase VIII
    Cellular localisation: Cytoplasm. Cell surface.
    Poids moléculaire
    32.97kDa
    ID gène
    767, 654388
    UniProt
    P35219
Vous êtes ici:
Support technique