CA8 anticorps (N-Term)

N° du produit ABIN965733

Détail du produit anti-CA8 anticorps

Antigène: CA8 (Carbonic Anhydrase VIII (CA8))

Épitope: N-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CA8 est non-conjugé

Application: Immunohistochemistry (IHC)

Purification: Purified by antigen-specific affinity chromatography.

Immunogène: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human CA8(Carbonic anhydrase VIII)

Information d'application

Indications d'application: ELISA, Western blotting: 1µg/ml for 2hrs.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: This antibody is stored in PBS, 50% glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Références pour anticorps anti-CA8 (ABIN965733)

Hirota, Ando, Hamada, Mikoshiba: "Carbonic anhydrase-related protein is a novel binding protein for inositol 1,4,5-trisphosphate receptor type 1." dans: The Biochemical journal, Vol. 372, Issue Pt 2, pp. 435-41, (2003) (PubMed).

Taniuchi, Nishimori, Takeuchi, Fujikawa-Adachi, Ohtsuki, Onishi: "Developmental expression of carbonic anhydrase-related proteins VIII, X, and XI in the human brain." dans: Neuroscience, Vol. 112, Issue 1, pp. 93-9, (2002) (PubMed).

Bergenhem, Sait, Eddy, Shows, Tashian: "Assignment of the gene for human carbonic anhydrase VIII(CA8) to chromosome 8q11-->q12." dans: Cytogenetics and cell genetics, Vol. 71, Issue 3, pp. 299-300, (1995) (PubMed).

Kelly, Nógrádi, Walker, Caddy, Peters, Carter: "Lurching, reeling, waddling and staggering in mice--is carbonic anhydrase (CA) VIII a candidate gene?" dans: Biochemical Society transactions, Vol. 22, Issue 3, pp. 359S, (1995) (PubMed).

Skaggs, Bergenhem, Venta, Tashian: "The deduced amino acid sequence of human carbonic anhydrase-related protein (CARP) is 98% identical to the mouse homologue." dans: Gene, Vol. 126, Issue 2, pp. 291-2, (1993) (PubMed).

Détails sur CA8

Antigène: CA8 (Carbonic Anhydrase VIII (CA8))

Autre désignation: CA8 (CA8 Produits)

Synonymes: anticorps AW546993, anticorps Ca8, anticorps Cals, anticorps Cals1, anticorps Carp, anticorps wdl, anticorps zgc:110118, anticorps CA-VIII, anticorps CALS, anticorps CAMRQ3, anticorps CARP, anticorps carbonic anhydrase 8, anticorps carbonic anhydrase VIII, anticorps CAH8, anticorps Car8, anticorps ca8, anticorps CA8

Sujet: CA8(Carbonic anhydrase VIII) was initially named CA-related protein because of sequence similarity to other known carbonic anhydrase genes. However, Carbonic anhydrase VIII lacks carbonic anhydrase activity (i.e., the reversible hydration of carbon dioxide). The Carbonic anhydrase VIII continues to carry a carbonic anhydrase designation based on clear sequence identity to other members of the carbonic anhydrase gene family. The absence of CA8 gene transcription in the cerebellum of the lurcher mutant in mice with a neurologic defect suggests an important role for this acatalytic form. Carbonic anhydrase VIII belongs to the eukaryotic-type carbonic anhydrase family.