CD34 anticorps

N° du produit ABIN6936665

Cet anticorps Souris Monoclonal détecte spécifiquement CD34 dans FACS, IF, ELISA et Coat. Il présente une réactivité envers Humain.

Aperçu rapide pour CD34 anticorps (ABIN6936665)

Antigène: CD34

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD34 est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (IF), ELISA, Coating (Coat)

Clone: ICO-115

Détail du produit anti-CD34 anticorps

Specificité: This antibody recognizes a carbohydrate epitope on a single chain, transmembrane, heavily glycosylated protein of 90-120kDa, which is identified as CD34 (VI international workshop on human differentiation antigens). Its expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, it is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. CD34 expression is also found in vascular endothelium. Additionally, proliferating endothelial cells overexpress this molecule than the non-proliferating endothelial cells. Anti-CD34 labels 85% of angiosarcoma and Kaposi's sarcoma, but shows low specificity.

Réactivité croisée (Details): Human. Rat.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Blast cells of a chronic myeloid leukemia patient

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Known_Application: ELISA (For coating, order antibody without BSA), Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.

Positive_Control: KG-1 cells. Human tonsil or angiosarcoma.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur CD34

Antigène: CD34

Autre désignation: CD34

Sujet: Hematopoietic Progenitor Cell Antigen, HPCA1, Mucosialin,CD34 (Hematopoietic Stem Cell & Endothelial Marker)
Cellular localisation: Cell surface

Poids moléculaire: 90-110kDa

ID gène: 947, 374990

UniProt: P28906