CD55 anticorps

N° du produit ABIN6936757

Cet anticorps anti-CD55 Monoclonal Souris (Clone F4-29D9) (ABIN6936757) détecte spécifiquement CD55 dans FACS et IF. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour CD55 anticorps (ABIN6936757)

Antigène: CD55 (Complement Decay-Accelerating Factor (CD55))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD55 est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: F4-29D9

Détail du produit anti-CD55 anticorps

Fonction: CD55 / Decay Accelerating Factor (DAF) Antibody

Specificité: Recognizes a single chain glycoprotein of 70 kDa, identified as CD55. This MAb was clustered in Kobe at the Sixth International Workshop on Human Leukocyte Differentiation Antigens as F429D-9 (N-L120). CD55/DAF is widely expressed on cells throughout the body including leukocytes, erythrocytes, epithelium, endothelium, and fibroblasts. It is a Glycosyl phosphatidylinositol anchored (GPI-anchored) member of the membrane bound complement regulatory proteins that inhibit autologous complement cascade activation. It prevents the amplification steps of the complement cascade by interfering with the assembly of the C3-convertases, C4b2a and C3bBb, and the C5-convertase, C4b2a3b and C3bBb3b. CD55 also serves as receptor for CD97 and for echovirus and Coxsackie B virus. Anti-CD55 can be used as marker for paroxysmal nocturnal hemoglobinuria (PNH).

Réactivité croisée (Details): Human.

Purification: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Human umbilical vein endothelial cells (HUVEC)

Isotype: IgG1, kappa

Information d'application

Indications d'application:

Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.

Positive_Control: Jurkat, HUT-78, K562, YT, U937, MG63 and human lymphocytes. Human lymph nodes and tonsils.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur CD55

Antigène: CD55 (Complement Decay-Accelerating Factor (CD55))

Autre désignation: CD55

Sujet:

CD55, CD55 Cromer blood group system, Complement decay-accelerating factor, CROM, DAF, Decay Accelerating Factor for Complement, Decay accelerating factor GPI-form, Decay accelerating factor soluble-form, GPI-DAF

HUT-78, Jurkat, K562, MG63 and human lymphocytes. Human lymph nodes and tonsils., U937, YT

Poids moléculaire: 70kDa

ID gène: 1604, 126517

UniProt: P08174

Pathways: Système du Complément, Regulation of Leukocyte Mediated Immunity