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CD68 anticorps (AA 150-221)

L’anticorps Souris Monoclonal anti-CD68 a été validé pour IHC (f). Il convient pour détecter CD68 dans des échantillons de Humain.
N° du produit ABIN6936792

Aperçu rapide pour CD68 anticorps (AA 150-221) (ABIN6936792)

Antigène

Voir toutes CD68 Anticorps
CD68 (CD68 Molecule (CD68))

Reactivité

  • 201
  • 68
  • 41
  • 34
  • 28
  • 16
  • 8
  • 5
  • 2
  • 2
  • 1
Humain

Hôte

  • 135
  • 90
  • 19
  • 1
Souris

Clonalité

  • 169
  • 71
  • 1
Monoclonal

Conjugué

  • 100
  • 17
  • 15
  • 10
  • 8
  • 8
  • 8
  • 8
  • 8
  • 8
  • 8
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp CD68 est non-conjugé

Application

  • 103
  • 102
  • 101
  • 69
  • 51
  • 35
  • 34
  • 32
  • 22
  • 18
  • 12
  • 8
  • 7
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Clone

C68-2511
  • Épitope

    • 24
    • 15
    • 13
    • 8
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 150-221

    Specificité

    This antibody recognizes a glycoprotein of 110 kDa, which is identified as CD68. It is important for identifying macrophages in tissue sections. It stains macrophages in a wide variety of human tissues, including Kupffer cells and macrophages in the red pulp of the spleen, in lamina propria of the gut, in lung alveoli, and in bone marrow. It reacts with myeloid precursors and peripheral blood granulocytes. It also reacts with plasmacytoid T cells, which are supposed to be of monocyte/macrophage origin. It shows strong granular cytoplasmic staining of chronic and acute myeloid leukemia and also reacts with rare cases of true histiocytic neoplasia. Lymphomas are negative or show few granules.

    Réactivité croisée (Details)

    Human.

    Purification

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    Immunogène

    Recombinant fragment of human CD68 protein (around aa 150-221) (exact sequence is proprietary)

    Isotype

    IgG2b kappa
  • Indications d'application

    Known_Application: Immunohistochemistry (Formalin-fixed) (0.25-0.5 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: Tonsil, Lymph Node or Spleen.

    Restrictions

    For Research Use only
  • Concentration

    1.0 mg/mL

    Buffer

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    Agent conservateur

    Azide free

    Stock

    -20 °C,-80 °C

    Stockage commentaire

    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    Date de péremption

    24 months
  • Antigène

    CD68 (CD68 Molecule (CD68))

    Autre désignation

    CD68

    Sujet

    GP110, LAMP4, Microsialin, Macrosialin, SCARD1, Scavenger Receptor Class D Member-1,CD68 (Macrophage Marker)
    Cellular localisation: Cell Surface and Cytoplasmic

    Poids moléculaire

    110kDa

    ID gène

    968, 647419

    UniProt

    P34810
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