Cytokeratin 1 anticorps
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- Antigène Voir toutes Cytokeratin 1 (KRT1) Anticorps
- Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Cytokeratin 1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF), Staining Methods (StM)
- Specificité
- Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. This antibody cocktail recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, which 67 kDa (CK1), 64 kDa (CK3), 59 kDa (CK4), 58 kDa (CK5), 56 kDa (CK6), 52 kDa (CK8), 56.5 kDa (CK10), 50 kDa (CK14), 50 kDa (CK15), 48 kDa (CK16), 40 kDa (CK19). Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. It is a broad spectrum anti pan-cytokeratin antibody, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer. It may be useful to characterize the source of various neoplasms and to study the distribution of cytokeratin containing cells in epithelia during normal development and during the development of epithelial neoplasms. This antibody stains cytokeratins present in normal and abnormal human tissues and has high sensitivity in the recognition of epithelial cells and carcinomas.
- Réactivité croisée (Details)
- Expected to show broad species reactivity.
- Immunogène
- Recombinant full-length human KRT76 and KRT77 proteins
- Isotype
- IgG
- Top Product
- Discover our top product KRT1 Anticorps primaire
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- Indications d'application
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Positive Control: Skin, Adeno- or Squamous carcinomas.
Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (0.5-1 μg/mL for 2 hours at RT), Immunohistochemistry (Formalin-fixed) (0.25-0.5 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
- Restrictions
- For Research Use only
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- Buffer
- 10 mM PBS without BSA and without Azide.
- Agent conservateur
- Azide free
- Stock
- 4 °C,-80 °C
- Stockage commentaire
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months.
- Date de péremption
- 24 months
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- Antigène
- Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))
- Autre désignation
- Cytokeratin (KRT1 Produits)
- Synonymes
- anticorps CK1, anticorps EHK, anticorps EHK1, anticorps EPPK, anticorps K1, anticorps KRT1A, anticorps NEPPK, anticorps Krt-2.1, anticorps Krt2-1, anticorps Krt86, anticorps KRT1, anticorps Kb1, anticorps KER1, anticorps CK-1, anticorps Keratin-1, anticorps keratin 1, anticorps KRT1, anticorps Krt1
- Poids moléculaire
- 40-67kDa
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