ENAH anticorps (AA 485-589)

N° du produit ABIN6937147

Cet anticorps anti-ENAH est un anticorps Souris Monoclonal détectant ENAH dans WB, ELISA et Coat. Adapté pour Humain.

Aperçu rapide pour ENAH anticorps (AA 485-589) (ABIN6937147)

Antigène: ENAH (Enabled Homolog (ENAH))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ENAH est non-conjugé

Application: Western Blotting (WB), ELISA, Coating (Coat)

Clone: ENAH-1988

Détail du produit anti-ENAH anticorps

Épitope: AA 485-589

Specificité: The Wiskott-Aldrich syndrome (WAS) is characterized by thrombocytopenia, eczema, defects in cell-mediated and humoral immunity and a propensity for lymphoproliferative diseases. The syndrome is the result of a mutation in the gene encoding a proline-rich protein termed WASP. WASP is a downstream effector of Cdc42 and has been implicated in actin polymerization and cyto- skeletal organization. Distantly related proteins, VASP (vasodilator-stimulated phosphoprotein) and Mena (for mammalian enabled protein), are involved in the regulation of cytoskeletal dynamics. Both Mena and VASP accumulate at focal adhesions. Mena is highly expressed in the developing nervous system and may be involved in growth cone motility and axon guidance.

Réactivité croisée (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Recombinant fragment of human MENA protein (around aa 485-589) (exact sequence is proprietary)

Isotype: IgG2c kappa

Information d'application

Indications d'application:

Known_Application: ELISA (For coating, order Ab without BSA),Western Blot (1-2 μg/mL), Optimal dilution for a specific application should be determined.

Positive_Control: MCF-7 cells. Uterus.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur ENAH

Antigène: ENAH (Enabled Homolog (ENAH))

Autre désignation: ENAH

Sujet: ENA, ENAH, MENA, NDPP1,ENAH / MENA (Actin Regulator)
Cellular localisation: Cytoplasmic

Poids moléculaire: 80/88/140kDa

ID gène: 55740, 497893

UniProt: Q8N8S7