HNF1A anticorps (AA 214-339)

N° du produit ABIN6937423

Cet anticorps anti-HNF1A Monoclonal Souris (Clone HNF1A-2087) (ABIN6937423) détecte spécifiquement HNF1A dans IHC et ELISA. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour HNF1A anticorps (AA 214-339) (ABIN6937423)

Antigène: HNF1A (HNF1 Homeobox A (HNF1A))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp HNF1A est non-conjugé

Application: Immunohistochemistry (IHC), ELISA

Clone: HNF1A-2087

Détail du produit anti-HNF1A anticorps

Épitope: AA 214-339

Fonction: HNF1A (Pancreatic Tumor Suppressor) Antibody

Specificité: HNF1A belongs to the homeobox protein family and is an essential transcription factor for many hepatic genes involved in detoxification, homeostasis and metabolisms of glucose, lipid, steroid and amino acid. In addition, HNF1A is an important component of the transcriptional networks governing embryonic pancreas development and differentiation. as well as maintaining the growth and function of islet cells in adult. HNF1A (Hepatocyte nuclear factor 1 alpha) is a transcription factor that is known to regulate pancreatic differentiation and maintain homeostasis of endocrine pancreas. Recently, genome-wide association studies have implicatedHNF1Aas a susceptibility gene for pancreatic cancer.

Réactivité croisée (Details): Human.

Purification: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant fragment (around aa 214-339) of human HNF1A protein (exact sequence is proprietary)

Isotype: IgG1, kappa

Information d'application

Indications d'application:

Known_Application: ELISA (For coating, order antibody without BSA),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

Positive_Control: Jurkat cells. Small Intestine or Pancreas.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur HNF1A

Antigène: HNF1A (HNF1 Homeobox A (HNF1A))

Autre désignation: HNF1A

Sujet:

Albumin proximal factor, Hepatic nuclear factor 1 alpha, Hepatic transcription factor 1 alpha, HNF-1A, Interferon production regulator factor, LFB1, LFB1 hepatic nuclear factor, Liver specific transcription factor LFB1, Maturity onset diabetes of the young 3 (MODY3), TCF1, Transcription factor 1 hepatic

Jurkat cells. Small Intestine or Pancreas.

Poids moléculaire: 79kDa

ID gène: 6927, 654455

UniProt: P20823

Pathways: Hormone Transport, Carbohydrate Homeostasis