HNF1A anticorps (AA 214-339)

N° du produit ABIN6937423

Détail du produit anti-HNF1A anticorps

Antigène: HNF1A (HNF1 Homeobox A (HNF1A))

Épitope: AA 214-339

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp HNF1A est non-conjugé

Application: ELISA, Coating (Coat), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Specificité: HNF1A belongs to the homeobox protein family and is an essential transcription factor for many hepatic genes involved in detoxification, homeostasis and metabolisms of glucose, lipid, steroid and amino acid. In addition, HNF1A is an important component of the transcriptional networks governing embryonic pancreas development and differentiation. as well as maintaining the growth and function of islet cells in adult. HNF1A (Hepatocyte nuclear factor 1 alpha) is a transcription factor that is known to regulate pancreatic differentiation and maintain homeostasis of endocrine pancreas. Recently, genome-wide association studies have implicatedHNF1Aas a susceptibility gene for pancreatic cancer.

Réactivité croisée (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Recombinant fragment (around aa 214-339) of human HNF1A protein (exact sequence is proprietary)

Clone: HNF1A-2087

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Known_Application: ELISA (For coating, order antibody without BSA),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

Positive_Control: Jurkat cells. Small Intestine or Pancreas.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur HNF1A

Antigène: HNF1A (HNF1 Homeobox A (HNF1A))

Autre désignation: HNF1A (HNF1A Produits)

Synonymes: anticorps HNF-1A, anticorps HNF1, anticorps IDDM20, anticorps LFB1, anticorps MODY3, anticorps TCF-1, anticorps TCF1, anticorps HNF-1a, anticorps AI323641, anticorps HNF1-alpha, anticorps HNF1[a], anticorps Hnf-1, anticorps Hnf1alpha, anticorps Tcf-1, anticorps Tcf1, anticorps HNF-1-alpha, anticorps HNF-1alpha, anticorps LF-B1, anticorps Lfb1, anticorps HNF-1, anticorps HNF1A, anticorps tcf1, anticorps FB1b, anticorps HNF1b, anticorps XLFB1b1, anticorps hnf1-B, anticorps lfb1b, anticorps mody3, anticorps tcf1-B, anticorps tcfb-A, anticorps HNF-1-alpha-A, anticorps HNF-1A-A, anticorps LFB1a1, anticorps TCF-1-A, anticorps XLFB1, anticorps XLFB1b, anticorps hnf1-a, anticorps hnf1a, anticorps hnf1a-a, anticorps hnf1a-b, anticorps hnf1a.L, anticorps tcf1-A, anticorps xx:af244934-22s, anticorps HNF1 homeobox A, anticorps HNF1 homeobox A L homeolog, anticorps HNF1 homeobox A S homeolog, anticorps HNF1 homeobox a, anticorps HNF1A, anticorps Hnf1a, anticorps hnf1a, anticorps hnf1a.L, anticorps hnf1a.S

Sujet: Albumin proximal factor, Hepatic nuclear factor 1 alpha, Hepatic transcription factor 1 alpha, HNF-1A, Interferon production regulator factor, LFB1, LFB1 hepatic nuclear factor, Liver specific transcription factor LFB1, Maturity onset diabetes of the young 3 (MODY3), TCF1, Transcription factor 1 hepatic,HNF1A (Pancreatic Tumor Suppressor)
Cellular localisation: Nuclear

Poids moléculaire: 79kDa

ID gène: 6927, 654455

UniProt: P20823

Pathways: Hormone Transport, Carbohydrate Homeostasis