KRT15 anticorps (C-Term)
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- Antigène Voir toutes KRT15 Anticorps
- KRT15 (Keratin 15 (KRT15))
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Épitope
- C-Term
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp KRT15 est non-conjugé
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Application
- Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- Specificité
- Keratin 15 is a type I keratin which is expressed only in basal keratinocytes in stratified epithelia and does not appear to have a natural type II expression partner. Keratin 15 is down regulated in activated keratinocytes. Cytokeratin 15 is a specific marker of stem cells of the hair-follicle bulge and may be a useful marker for diagnosis between basal cell carcinoma (BCC) and trichoepithelioma. Trichoblastoma are benign neoplasms of follicular differentiation frequently found in nevus sebaceous. Many morphologic features are shared with nodular basal cell carcinoma, sometimes rendering a diagnosis difficult. Trichoblastoma and BCC show variable expression of Cytokeratin 15 and Cytokeratin 19, and absence of hair keratins.
- Réactivité croisée (Details)
- Human. Rat. Cow.
- Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogène
- A 17 amino acids synthetic peptide from the C- terminal of Human Cytokeratin 15
- Clone
- LHK15
- Isotype
- IgG2a kappa
- Top Product
- Discover our top product KRT15 Anticorps primaire
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- Indications d'application
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Known_Application: Immunohistochemistry (Formalin-fixed) (0.1-0.2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: A431 cells. Skin or Colon.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Agent conservateur
- Azide free
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Date de péremption
- 24 months
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- Antigène
- KRT15 (Keratin 15 (KRT15))
- Autre désignation
- KRT15 (KRT15 Produits)
- Synonymes
- anticorps xlk2, anticorps CK15, anticorps K15, anticorps K1CO, anticorps AI528832, anticorps Krt1-15, anticorps Ka15, anticorps wu:fa91c06, anticorps wu:fa95d04, anticorps zgc:55334, anticorps keratin 15, type I L homeolog, anticorps keratin 15, type I, anticorps keratin 15, anticorps krt15.L, anticorps krt15, anticorps KRT15, anticorps Krt15
- Sujet
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CK15, Cytokeratin 15, K1CO, Ka15, Keratin 15 basic, Keratin 15 beta, Keratin complex 1 acidic gene 15, Keratin type I cytoskeletal 15, KRT15, KRTB, KRTL15, Type I cytoskeletal 15, Type I keratin Ka15,Cytokeratin 15 (Esophageal Squamous Cell Carcinoma Marker)
Cellular localisation: Cytoplasmic - Poids moléculaire
- 52kDa
- ID gène
- 3866, 654570
- UniProt
- P19012
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