Recombinant Cytokeratin 18 anticorps
Aperçu rapide pour Recombinant Cytokeratin 18 anticorps (ABIN6937689)
Antigène
Voir toutes Cytokeratin 18 (KRT18) AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- This MAb reacts with a wide variety of simple epithelia. It does not react with stratified squamous epithelia. It reacts with epithelial tumors of the gastrointestinal tract, lung, breast, pancreas, ovary, and thyroid. Cytokeratin 18, which belongs to the type A (acidic) subfamily of low molecular weight keratins, exists in combination with cytokeratin 8. It was reported that tissues from gastrointestinal tract are positive for both cytokeratin 8 and 18 but do not contain cytokeratin 14. Tissues from gastrointestinal tract, respiratory tract and urogenital tract, as well as endocrine and exocrine tissues and mesothelial cells are positive for cytokeratin 18.
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Aucune reactivité croisée
- Poulet, Xenopus laevis
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Réactivité croisée (Details)
- Human. Mouse. Rat. Hamster. Ferret. Cow. Pig. Cat. Dog. Sheep. Goat. Horse. Marmoset monkey. Does not react with Chicken or Xenopus.
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Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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Immunogène
- Recombinant human full-length KRT18 protein
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Isotype
- IgG
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Indications d'application
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Known_Application: Flow Cytometry (1-2 μg/million cells),Western Blot (1-2 μg/mL),Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: HCT116, MCF-7, HeLa cells, Breast Cancer.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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Agent conservateur
- Azide free
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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Date de péremption
- 24 months
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- Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))
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Autre désignation
- KRT18
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Sujet
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Cell Proliferation-inducing Gene 46 Protein, CK18, CYK18Cytokeratin Endo B, K18, Keratin-18, Kerd, KRT18,Cytokeratin 18 (KRT18)
Cellular localisation: Cytoplasmic -
Poids moléculaire
- 45kDa
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ID gène
- 3875, 406013
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UniProt
- P05783
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Pathways
- Apoptose, Caspase Cascade in Apoptosis
Antigène
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