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LGALS13 anticorps (AA 23-134)

LGALS13 Reactivité: Humain FACS, IF, WB, IHC (f) Hôte: Souris Monoclonal PP13-1161 unconjugated
N° du produit ABIN6937776
  • Antigène Voir toutes LGALS13 Anticorps
    LGALS13 (Lectin, Galactoside-Binding, Soluble, 13 (LGALS13))
    Épitope
    • 17
    • 3
    • 1
    • 1
    • 1
    AA 23-134
    Reactivité
    • 24
    • 1
    Humain
    Hôte
    • 20
    • 4
    Souris
    Clonalité
    • 18
    • 6
    Monoclonal
    Conjugué
    • 10
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp LGALS13 est non-conjugé
    Application
    • 19
    • 15
    • 15
    • 15
    • 10
    • 9
    • 2
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunofluorescence (IF), Western Blotting (WB), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    Specificité
    It recognizes a 32 kDa protein, which is identified as homodimer of galectin-13 (also known as PP13). Galectins are a family of soluble -galactoside-binding lectins that modulate cell-to-cell adhesion and cell-to-extracellular matrix (ECM) interactions and play a role in tumor progression, pre-mRNA splicing and apoptosis. One such member, galectin-13, is a 139 amino acid protein that contains one galectin domain. Possessing lysophospholipase activity, galectin-13 exists as a disulfide-linked homodimer. Galectin-13 is suggested to have a developmental role in the placenta and may display immunobiological activity in feto-maternal blood-spaces. Screening for galectin-13 in maternal serum during the first trimester of pregnancy may serve as a diagnostic marker to predict preterm pre-eclampsia.
    Réactivité croisée (Details)
    Human.
    Purification
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    Immunogène
    Recombinant human Galectin-13 protein fragment (aa23-134)
    Clone
    PP13-1161
    Isotype
    IgG2b kappa
    Top Product
    Discover our top product LGALS13 Anticorps primaire
  • Indications d'application

    Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: K-562 cells. Placenta or Spleen.

    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    Agent conservateur
    Azide free
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    Date de péremption
    24 months
  • Antigène
    LGALS13 (Lectin, Galactoside-Binding, Soluble, 13 (LGALS13))
    Autre désignation
    LGALS13 (LGALS13 Produits)
    Synonymes
    anticorps GAL13, anticorps PLAC8, anticorps PP13, anticorps Gal-11, anticorps Gal-13, anticorps Gal11, anticorps gal-13, anticorps galectin 13, anticorps avian beta-defensin 13, anticorps LGALS13, anticorps AvBD13
    Sujet
    Gal-13, GAL13, Galactoside-binding soluble lectin 13, Galectin-13, Galectin13, Lectin galactoside binding soluble 13, LGALS13, PLAC8, Placental protein 13 (PP13), Placental tissue protein 13,Galectin-13 (GAL13) / Placental Protein 13 (PP13)
    Cellular localisation: Cytoplasmic & Cell Surface
    Poids moléculaire
    16kDa (monomer), 32kDa (homodimer)
    ID gène
    29124, 23671
    UniProt
    Q9UHV8
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