Recombinant LMO2 anticorps (AA 23-140)

N° du produit ABIN6937787

Détail du produit anti-LMO2 anticorps

Antigène: LMO2 (LIM Domain Only 2 (Rhombotin-Like 1) (LMO2))

Type d'anticorp: Recombinant Antibody

Épitope: AA 23-140

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp LMO2 est non-conjugé

Application: Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Specificité: The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. It has a particular function in normal and lymphatic endothelial cells involving the regulation of angiogenesis and lymph-angiogenesis. Immunohistochemical studies have also demonstrated expression of LMO2 in both normal germinal center B-cells and germinal center-derived B-cell lymphomas, including follicular lymphoma and diffuse large B-cell lymphoma.The use of anti-LMO2 is valuable as a tool in the identification of lymphomas of B-cell origin. LMO2 is useful in differentiating follicular lymphoma (LMO2+) from nodal marginal zone lymphoma (LM02-). It also is positive in Hodgkin s and Burkitt s lymphomas.

Réactivité croisée (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Recombinant human LMO2 protein fragment (around aa 23-140) (exact sequence is proprietary)

Clone: RLMO2-1971

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

Positive_Control: K562, Ramos or Raji cells. Placenta, pancreas or Hodgkin s lymphoma.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur LMO2

Antigène: LMO2 (LIM Domain Only 2 (Rhombotin-Like 1) (LMO2))

Autre désignation: LMO2 (LMO2 Produits)

Synonymes: anticorps Rbtn-2, anticorps Rbtn2, anticorps Rhom-2, anticorps Ttg2, anticorps RBTN2, anticorps RBTNL1, anticorps RHOM2, anticorps TTG2, anticorps wu:fc83a08, anticorps zgc:111930, anticorps LMO-2, anticorps lmo2-A, anticorps xlmo2, anticorps rhombotin-2, anticorps LIM domain only 2, anticorps LIM domain only 2 (rhombotin-like 1), anticorps LIM domain only 2 S homeolog, anticorps lmo2, anticorps LMO2, anticorps Lmo2, anticorps lmo2.S

Sujet: Cysteine-rich protein TTG-2, LIM domain only protein 2, LMO-2, RBTN L1, RBTN2, Rhombotin like 1, Rhombotin-2 (RHOM2), T-cell translocation protein 2, TTG2,LMO2 (B-Cell Marker)
Cellular localisation: Nuclear

Poids moléculaire: 24kDa

ID gène: 4005, 34560

UniProt: P25791

Pathways: Chromatin Binding