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LMO2 anticorps (AA 23-140)

Cet anticorps anti-LMO2 est un anticorps Souris Monoclonal détectant LMO2 dans WB, FACS et IHC (f). Adapté pour Humain.
N° du produit ABIN6937789

Aperçu rapide pour LMO2 anticorps (AA 23-140) (ABIN6937789)

Antigène

Voir toutes LMO2 Anticorps
LMO2 (LIM Domain Only 2 (Rhombotin-Like 1) (LMO2))

Reactivité

  • 73
  • 12
  • 9
  • 6
  • 6
  • 6
  • 5
  • 4
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
Humain

Hôte

  • 43
  • 29
  • 2
Souris

Clonalité

  • 43
  • 31
Monoclonal

Conjugué

  • 41
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
Cet anticorp LMO2 est non-conjugé

Application

  • 46
  • 38
  • 25
  • 23
  • 20
  • 11
  • 5
  • 2
  • 2
  • 2
  • 1
Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Clone

LMO2-1971
  • Épitope

    • 33
    • 9
    • 6
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 23-140

    Specificité

    The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. It has a particular function in normal and lymphatic endothelial cells involving the regulation of angiogenesis and lymph-angiogenesis. Immunohistochemical studies have also demonstrated expression of LMO2 in both normal germinal center B-cells and germinal center-derived B-cell lymphomas, including follicular lymphoma and diffuse large B-cell lymphoma.The use of anti-LMO2 is valuable as a tool in the identification of lymphomas of B-cell origin. LMO2 is useful in differentiating follicular lymphoma (LMO2+) from nodal marginal zone lymphoma (LM02-). It also is positive in Hodgkin s and Burkitt s lymphomas.

    Réactivité croisée (Details)

    Human.

    Purification

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    Immunogène

    Recombinant human LMO2 protein fragment (around aa 23-140) (exact sequence is proprietary)

    Isotype

    IgG2b kappa
  • Indications d'application

    Known_Application: Flow Cytometry (1-2 μg/million cells), Western Blot (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: K562, Ramos or Raji cells. Placenta, pancreas or Hodgkin s lymphoma.

    Restrictions

    For Research Use only
  • Concentration

    1.0 mg/mL

    Buffer

    Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

    Agent conservateur

    Azide free

    Stock

    -20 °C,-80 °C

    Stockage commentaire

    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    Date de péremption

    24 months
  • Antigène

    LMO2 (LIM Domain Only 2 (Rhombotin-Like 1) (LMO2))

    Autre désignation

    LMO2

    Sujet

    Cysteine-rich protein TTG-2, LIM domain only protein 2, LMO-2, RBTN L1, RBTN2, Rhombotin like 1, Rhombotin-2 (RHOM2), T-cell translocation protein 2, TTG2,LMO2 (B-Cell Marker)
    Cellular localisation: Nuclear

    Poids moléculaire

    24kDa

    ID gène

    4005, 34560

    UniProt

    P25791

    Pathways

    Chromatin Binding
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