Recombinant Mammaglobin A anticorps

N° du produit ABIN6937804

Cet anticorps anti-Mammaglobin A Monoclonal Lapin (Clone MGB-2123R) (ABIN6937804) détecte spécifiquement Mammaglobin A dans IHC. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Recombinant Mammaglobin A anticorps (ABIN6937804)

Antigène: Mammaglobin A (SCGB2A2) (Secretoglobin, Family 2A, Member 2 (SCGB2A2))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Mammaglobin A est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: MGB-2123R

Détail du produit anti-Mammaglobin A anticorps

Fonction: Recombinant Mammaglobin (SCGB2A2) (Breast Cancer Marker) Antibody

Specificité: Mammaglobin is a 93 amino acid glycoprotein with homology to other secretoglobin-uteroglobin family members. It was originally identified as a breast cancer restricted biomarker by differential screening. Mammaglobin related to secretoglobin family that includes human uteroglobin and lipophilin. Mammaglobin antibody stains cytoplasm of normal breast epithelial cells as well as primary and metastatic breast carcinomas. Mammaglobin expression is absent in prostate, kidney, colon, rectum, small intestine, stomach, pancreas, lung, and thyroid tissues.Mammaglobin may be used as part of an immunohistochemical panel for determination of metastatic breast carcinoma and tumor of unknown primary origin.

Réactivité croisée (Details): Human.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant full-length human SCGB2A2 (Mammaglobin-1) protein

Isotype: IgG, kappa

Information d'application

Indications d'application:

Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Positive_Control: HeLa or MCF-7 cells. Mammary gland specific. Overexpressed in breast cancer.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur Mammaglobin A

Antigène: Mammaglobin A (SCGB2A2) (Secretoglobin, Family 2A, Member 2 (SCGB2A2))

Autre désignation: Mammaglobin (SCGB2A2) (Breast Cancer Marker)

Sujet:

Mammaglobin-1 (MGB1), Mammaglobin-A, Secretoglobin family 2A member 2 (SCGB2A2), SG2A2, UGB2

HeLa or MCF-7 cells. Mammary gland specific. Overexpressed in breast cancer.

Poids moléculaire: 18kDa

ID gène: 4250, 46452

UniProt: Q13296